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#Post#: 869--------------------------------------------------
Parkinsons Disease
DIR By: AGelbert
Date: February 20, 2023, 12:54 pm
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HTML https://soberthinking.createaforum.com/gallery/soberthinking/1-200223135633.png
Feb 17, 2023
[center]Partnering with Morehouse School of Medicine to
Diversify Genetic Data[/center]
SNIPPETS:
[glow=green,2,300]Chantale Branson, MD[/glow], is the first-ever
movement disorders specialist — a neurologist with specialized
training — to work at Morehouse School of Medicine in Atlanta,
GA. In addition to treating and helping people with Parkinson’s
disease (PD), she is committed to improving the health
disparities that Black and African American individuals face in
the PD community.
Under Dr. Branson’s direction, Morehouse is the first
historically Black institution of medicine to become a PD
GENEration: Mapping the Future of Parkinson’s Disease research
site. Every research site works alongside the Parkinson’s
Foundation to offer genetic testing and counseling to people
with PD, in English or Spanish, at no cost. ... ...
Acknowledging [glow=red,2,300]History[/glow] to Create
[glow=green,2,300]Change[/glow]
Today there are numerous regulations in place set to ensure
clinical trials follow ethical practices, but this was not
always the case. “Due to the historical issues and in regard to
race in the United States, research has not been very common
within the community, particularly within different diseases
such as the Parkinson’s disease and neurological disorders,”
said Dr. Branson.
The notorious [glow=red,2,300]Tuskegee study[/glow] that was
reported nearly 50 years ago, where researchers withheld
detrimental treatments from hundreds of Black men in Alabama for
decades, is still top of mind when it comes to distrust in
medicine and research among Black and African Americans.
Dr. Branson also references the story of Henrietta Lacks, a
Black woman who died of cervical cancer in 1951. Tissue samples
of her cancerous cells were given to a researcher and shared
with others without Henrietta’s knowledge or informed consent —
a historical lesson that is now a staple of medical ethics.
Known today as HeLa cells, these cells remain a vital tool in
disease research due to their ability to endure and replicate in
the laboratory.
Openly discussing these and the other historical wrongs of
medical and research communities, as well as reminding patients
of the safeguards in place that help protect them in research
studies are cornerstones for how Dr. Branson practices medicine.
“Sometimes patients may have preconceived notions or ideas about
the clinical research history within the Black community. Having
that conversation about understanding the
[glow=red,2,300]past[/glow] in order to discuss the
😕🤔 present is very important,” said
[glow=green,2,300]Dr. Branson[/glow].
Read more:
HTML https://soberthinking.createaforum.com/gallery/soberthinking/1-040422164555-532108.png
HTML https://www.parkinson.org/blog/research/morehouse-school-medicine
#Post#: 1015--------------------------------------------------
Re: Parkinsons Disease ► Alpha-synuclein seed
amplification assay detected early Parkinson’s 87% of the time.
DIR By: AGelbert
Date: April 26, 2023, 11:19 am
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HTML https://soberthinking.createaforum.com/gallery/soberthinking/1-200223135633.png
April 26, 2023
[center]
HTML https://ci6.googleusercontent.com/proxy/gnJ7Lr_yBdbgRXgXQdTTOcORHCkjntAt3RjWmDCZnnYhNl2jPy2xZdTRIzsY4CwfWkoxKuc-NjvqmGM2-r2Gda1reRXyxgLq1tHDUoSn5m-0omyvcIvagi_FMA=s0-d-e1-ft#http://www3.parkinson.org/images/content/pagebuilder/ScienceNewsHero.jpg[/center]
SNIPPET:
A recent study adds promising new data to support a test that
may allow Parkinson’s disease (PD) to be diagnosed before
symptoms appear.
Central to Parkinson’s, a protein called alpha-synuclein helps
brain cells function. When these proteins misfold (meaning they
are not shaped properly) they cannot function normally. Certain
types of misfolded alpha-synuclein act as “seeds” that spread,
much like a red sock in the washing machine can turn everything
pink. When these misfolded proteins clump together, they
eventually kill brain cells, and PD symptoms appear.
[center][img
width=640]
HTML https://www.parkinson.org/sites/default/files/styles/380x361/public/images/Seed-Amplification-Assay-Blog.webp?itok=UGA8lII8[/img][/center]
[center]Brain Scan[/center]
The Study
By the time a doctor makes a Parkinson’s diagnosis, the disease
has most likely progressed for years. However, a recent study
adds promising new data to support a new diagnostic test. The
study builds on prior research, using a test called an
alpha-synuclein seed amplification assay (SAA) that
distinguishes between people who do or do not have Parkinson’s.
The new study found that:
► Alpha-synuclein seed amplification assay detected early
Parkinson’s 87% of the time.
► In volunteers who did not have Parkinson’s, the test
showed the absence of the disease 96% of the time.
The test’s ability to detect Parkinson’s using misfolded protein
measurements make it a promising potential tool, but what does
this study mean to people with PD right now?
Full article:
HTML https://www.parkinson.org/blog/science-news/seed-amplification-assay
December 30, 2022
SNIPPET:
Air pollutants include gases and particulate matter, or
microscopic solids or liquid droplets. Pollutant gases include
nitrogen dioxide and black carbon, which are derived mostly from
the burning of fossil fuel, and ozone, which results from
pollutants emitted from cars, power plants, refineries, and
chemical plants.
Full article:
HTML https://soberthinking.createaforum.com/gallery/soberthinking/1-040422164555-532108.png
[center]Long-term Exposure to Air
[glow=red,2,300]Pollution[/glow] Tied to Parkinson’s
[glow=maroon,2,300]☠️ Mortality[/glow]
HTML https://parkinsonsnewstoday.com/news/long-term-exposure-air-pollution-linked-parkinsons-mortality/<br
/>
HTML https://soberthinking.createaforum.com/gallery/soberthinking/1-040622202720-1408267.gif[/center]
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