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       #Post#: 11949--------------------------------------------------
       Genetic Testing
       By: Cliff Ball Date: November 21, 2012, 11:09 am
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       As Vice-President of the NBRC, and as an individual fancier, I
       have taken it upon myself to investigate the potential for
       genetic background strain characterization of the Birmingham
       Roller. We are interested in developing a custom genotyping
       assay designed to suit our needs in the pursuit of genotyping
       aimed at the identification and confirmation of background
       strains for the purposes of establishing breed standards and
       detecting misbreedings and pedigree errors. The goal is to
       establish microsatellite repeat (short tandem repeat, STR)
       markers that can quickly, easily and inexpensively identify a
       genetically contaminated mating event, as well as possibly
       including the detection of ancestral misbreeding.
       Once background strain characterization has been completed, we
       can proceed with some of the following pursuits:
       1.      The establishment of a genetically-assisted breed
       standard for the vast majority of fanciers who wish to establish
       closed breedings.
       2.      The identification of strains and sub-families; both
       established and newly-developed.
       3.      The identification of hybrid vigor.
       4.      Monitoring established breeding colonies and lofts.
       5.      Identifying genetic drift and assessing the loss of
       heterozygosity within breeding lofts, thus assisting with
       breeding management.
       6.      Periodic genetic characterization to ensure strain/line
       purity in breeding programs.
       7.      Assessing allele frequencies, heterozygosity, and
       relatedness in outbred populations
       It is our hope that genetic background characterization will
       alert breeders to errors in pedigrees, to genetic variation and
       mutation that may occur in closed breeding programs, as well as
       in the identification of contaminated genetic backgrounds
       through misbreeding.
       As a secondary more complex goal, our objective is also to lay
       the groundwork for the identification of the complex gene
       interactions responsible for the phenomenon of spinning in
       flight with the goal of identifying genetic markers for optimum
       performance.
       Consistent with this effort, the scientific team has  indicated
       that we need to identify a family or two of Birmingham Rollers
       that has been linebred and inbred as purely as possible. I would
       appreciate any suggestions as to your recommendation of the most
       pure family available. We would need to collect blood samples
       from toe-nail clippings of about 30 birds for the initial study.
       The Starleys. Billings, and Doucet birds come to mind, but I am
       open to suggestions. Secondly we need to select a subfamily that
       might represent the substrain or family that we would expect to
       be, genetically, close, but potentially most diverse from the
       “pure” family. I suggest the Turner indigo.andalusian family to
       represent this class. And thirdly, we need to select a couple of
       families that represent the breed, but that have been outcrossed
       to other families in their creation. The Jaconettes, Reed, Ruby
       Rollers,and Higgins birds come to mind, and possibly the Mees
       and Hatcher /Continentals, but I stand to be corrected, being
       unsure as to the development of some of these families. I
       appreciate your input. You may contact me by private e-mail if
       you prefer……
       Cliff
       
       #Post#: 11950--------------------------------------------------
       Re: Genetic Testing
       By: Tony Chavarria Date: November 22, 2012, 7:52 am
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       Cliff, an awesome project! Count me and the Ruby strain in! I
       have been giving much thought to the impact of environment on
       phenotype,  specifically performance.  I am doing research on
       this and it will be included in my rewrite of my publication
       "How To Breed Better Rollers". Let me know how I can help.
       #Post#: 11951--------------------------------------------------
       Re: Genetic Testing
       By: Cliff Ball Date: November 22, 2012, 8:12 am
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       Excellent, Tony. I am getting some fears expressed, that the
       data will be mis-used for monetary gain...will ruin the sport,
       etc.I ask, "Has genetic testing improved the prosecution of the
       guilty in our courts? Has it freed the innocent who have been
       behind bars? Has it helped to identify the dead-beat dad?" I
       understand the fears that knowldege may bring to some.
       Cliff
       #Post#: 11952--------------------------------------------------
       Re: Genetic Testing
       By: Tony Chavarria Date: November 22, 2012, 10:30 am
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       Cliff, to the naysayers "lead - follow or get out of the way".
       Nothing improves without innovation. Most innovation happens
       because someone usually will profit from it. So what? Who says
       they get to frame the debate? Don't be a wuss man just do it.
       LOL
       #Post#: 11958--------------------------------------------------
       Re: Genetic Testing
       By: donnie james Date: November 22, 2012, 6:41 pm
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       hay cliff
       i'm dialysis now and i'm tired biggest part of the  time why
       don't you make short and sweet for me so i can't  get so tire
       writing your long post donnie james
       #Post#: 11961--------------------------------------------------
       Re: Genetic Testing
       By: Sound Rollers Date: November 22, 2012, 8:23 pm
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       Hey Cliff, my birds are pure Norm Reed birds. His birds were
       pure Houghton blood, made up of David Sanchez, Richard Espinoza,
       Ron Kumro from Long Island, Joe Houghton, Rusty Houghton and
       Homer Corderre.
       John
       
       #Post#: 11964--------------------------------------------------
       Re: Genetic Testing
       By: Cliff Ball Date: November 23, 2012, 6:21 pm
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       Excellent, John. We are looking for several classes (famlies) of
       pigeons. 1.Birds from a family that is as "pure" a single strain
       (family) as possible, going back to the original imports or the
       old families of English birds. 2. Birds from a family that still
       appears to be part of the breed, but has a known breed outcross
       somewhere in its distant past.3. Birds from famliles of rollers
       that were created by crossing several other families....to see
       if there are any genetic differences from the single family
       strains. Your family would fit into the third category, nicely,
       as I believe the Rubys would. Refresh my memory, if you will
       Tony, as to the foundations families behind the Rubys.
       Cliff
       #Post#: 11966--------------------------------------------------
       Re: Genetic Testing
       By: samir Date: November 24, 2012, 8:17 am
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       Is this goig to be DNA testings?
       #Post#: 11968--------------------------------------------------
       Re: Genetic Testing
       By: Cliff Ball Date: November 24, 2012, 10:07 pm
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       Yes....
       Cliff
       #Post#: 11969--------------------------------------------------
       Re: Genetic Testing
       By: samir Date: November 24, 2012, 10:16 pm
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       Interesting.  I personaly like genetics, and experiments.  Do
       you plan to have a site on internet where plan, progres and
       results of this tests will be published?
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