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CORONAVIRUS MEDICATION DISCUSSION
DIR By: Road2HardCoreIron
Date: March 27, 2020, 12:40 pm
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IMPORTANT: Coronavirus medications
As with any medication talk to doctors, read good research
before making any decisions. I will list the medications we hope
to carry soon. But YOU should do your homework before
selectioning. Upon rising Request list has grown for this
product almost as quick as the virus. I remain bipartisan on
this drug for the COVID-19 use. Just remember do not treat any
meds we carry as you would homemade products. The sad thing is
there are some who will pirate this drug. This is the world we
live in. I won’t let that happen here. If we provide it it will
be real. Here’s whst we hope to carry very soon. Those on list
will be first unless your family is in harm. I’m human and do
care. $$$ helps but comes second to someone’s life. Anyone that
dealt with me knows my compassion to make one’s life better.
Greed is what destroys us. BEAWARE OF FAKES! NO ONE CAN PRODUCE
THIS PRODUCT. BEWARE OF FALSE LABING.
(STAY SAFE REMAIN IN A SAFE PLACE)
Aralen 200 mg
HCQS 500 mg
Lariago 250 mg
Lariago 500
Hydroxychloroquine, chloroquine and other potential COVID-19
treatments explained
Darrell Etherington
@etherington / 3:37 pm EDT • March 20, 2020
FRANCE-CHINA-HEALTH-VIRUS
Image Credits: GERARD JULIEN / Getty Images
During two of this week’s White House briefings, President Trump
referred specifically to two potential treatments that have been
identified by medical researchers and clinicians, and that have
undergone various degrees of investigation and testing in the
ongoing fight against the global coronavirus pandemic. It’s
important to note upfront that regardless of what you may have
heard, from Trump or any other sources, no drugs or treatments
have been proven as effective for either the prevention of
contracting COVID-19 or for its treatment.
That said, a number of different clinical studies are currently
in progress all over the world, and in the U.S., the National
Institutes of Health is looking to fill a 400-volunteer study
that will provide clinical results related to use of remdesivir,
an antiviral drug developed by Gilead originally as a treatment
for Ebola, but it’s still only in clinical trials even for
treatment of that disease. This study could also add other drug
candidates as additional test therapies. Meanwhile, studies in
China and France have examined the effectiveness of
anti-malarial drugs, including chloroquine and
hydroxychloroquine — including one small-scale study that
suggests the positive effects of hydroxycholoroquine in reducing
both the duration and symptoms of COVID-19 in combination with
an antibiotic called azithromycin.
The important thing to keep in mind when considering these or
any other potential treatments for the novel coronavirus, which
is still relatively young, is that a lot of what we know about
them so far is effectively anecdotal, and based not on the kind
of scientifically rigorous controlled clinical studies that are
normally used in the years-long development and certification of
drugs. Instead, treatments like remdesivir and
chloroquine/hydroxychloroquine are being deployed in the field
by healthcare practitioners based on their approved use in
similar (but crucially not the same) situations, like the Ebola
and SARS outbreaks.
Often, they’re being used under what’s called “compassionate”
grounds in the U.S. This effectively amounts to employing a drug
that’s not yet certified for general use in treatment of a
patient whose condition is so severe that a doctor is willing to
go to desperate lengths to try to alleviate their symptoms. This
has the advantage of sidestepping typical testing and approval
procedures, and requiring that the results of its use are
documented, which contributes to the overall body of clinical
knowledge in terms of its effects and interactions with patients
and with COVID-19.
It’s not a clinical study, however, and that means there are
still a lot of unknowns when it comes to its use that just can’t
be learned or asserted based on scattered, individual instances
of compassionate care treatment.
“As the Commissioner of FDA and the president mentioned
yesterday, we’re trying to strike a balance between making
something with the potential of an effect available to the
American people, at the same time that we do it under the
auspices of a protocol that would give us information to
determine if it’s truly safe and truly effective,” explained
National Institute of Allergy and Infectious Diseases Director
Dr. Anthony Fauci during a press conference on Friday. “But the
information that you’re referring to specifically is anecdotal,
it was not done in a controlled clinical trial. So you really
can’t make any definitive statement about it.”
During Thursday’s White House coronavirus pandemic task force
briefing, Trump made false claims that chloroquine was already
approved by the FDA as a treatment for COVID-19 under an
emergency authorization. FDA Director Dr. Stephen Hahn clarified
that this and remdesivir were being considered and studied by
the FDA, as was an approach that would use plasma extracted from
patients who’d recovered from COVID-19, as a potential source of
antibodies for others. Still, all of these are still quite far
away from clinical deployment in any generally approved way.
Meanwhile, Fauci’s cautions should be taken for what they are:
Warnings that are primarily meant to emphasize that the reason
the FDA requires clinical studies, even for drugs already
tentatively approved for use in other cases, is because it has
patient health and safety in mind. While chloroquine has been
used for decades to treat malaria, and chronic rheumatoid
arthritis, it can have dangerous side effects, including death,
if taken incorrectly. Even when taken correctly, it can cause
things like stomach distress, and even permanent damage to a
person’s vision.
Fauci’s comments Friday explain the risks of putting too much
stock in any potential treatment at this stage, even if they are
showing promising results among small or even medium-sized
deployments.
“You’ve got to be careful when you say ‘fairly effective,’ it
was never done in a clinical trial that compared it to
anything,” he said in answer to a reporter’s question about
chloroquine’s efficacy in treating SARS. “It was given to
individuals and felt that maybe it worked […] Whenever you do a
clinical trial, you do standard of care, versus standard of care
plus the agent you’re evaluating. That’s the reason why we
showed back in Ebola why particular interventions worked.”
A summary survey of various prospective treatments and their
current status was published today In Medscape, and this
includes the current state of remdesivir and chloroquine
investigations, as well as a number of other drugs being studied
by researchers. As has been reported here and elsewhere, there
are promising signs that they could prove effective in either
treatment, or treatment and even preventative use (in the case
of remedesivir), but these are, as Dr. Fauci puts it, only the
first step that should lead to more sophisticated clinical
studies, which themselves will then need competing peer studies
to eventually prove out.
Last edited by ESTROGEN GUY; 03-22-202
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