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       Russia's Wizard Created Drug Cocktail  (Milos Sarcev) Invovled
       By: Road2HardCoreIron Date: September 20, 2025, 4:12 pm
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       This board does not condone the use of any medication. Members
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       MOSCOW Even as he worked to cover up doping by Russian athletes,
       Grigory Rodchenkov was developing technology which would help to
       catch them years later.
       The former head of the Moscow anti-doping laboratory is the star
       witness for the World Anti-Doping Agency investigator Richard
       McLaren, whose report Friday accused Russia of operating a
       state-backed doping program which covered up more than 1,000
       tainted drug test samples, including for medalists at the 2014
       Winter Olympics.
       However, Rodchenkov’s role in helping catch drug cheats isn’t
       widely known outside a small circle of the world’s leading
       anti-doping scientists.
       Methods devised by Rodchenkov and his former assistant at the
       lab, Timofei Sobolevsky, to detect two common steroids have
       become a crucial weapon for drug testers in a wave of retesting
       carried out this year by the International Olympic Committee,
       though some dispute the Russians’ work.
       So far, 62 athletes — almost half of them Russians — have been
       disqualified from the 2008 and 2012 Olympics in IOC retests
       after testing positive for turinabol, a banned substance which
       Rodchenkov helped make much easier for labs to find in samples.
       There are also six cases involving oxandrolone, another steroid
       on which Rodchenkov carried out research, though all but one of
       those also tested positive for turinabol, a black-market steroid
       developed in the old East Germany which bulks up muscle and has
       plagued global sport for decades.
       “Even if they are old and quite well known substances, there is
       continuous research on the metabolic behavior of these
       substances,” said Tiia Kuuranne, head of the laboratory in
       Lausanne, Switzerland, which handles retests for the
       International Olympic Committee.
       “These advances are the ones that lead to these kinds of
       breakthroughs or leaps in doping control.”
       Those who tested positive for turinabol in IOC retesting
       competed for 10 different countries, mostly in the former Soviet
       Union, and range from Kazakhstan’s Ilya Ilyin, who used his
       record-breaking weightlifting career to build a following of
       400,000 on Instagram, to a Belarusian runner and a Russian
       wrestler. Many of them deny doping, including Ilyin.
       The key advance was the discovery of new turinabol metabolites,
       the chemical traces left when complex steroids break down in the
       human body. Turinabol produces a wide range of metabolites, some
       of them quickly flushed out of a doped athlete’s system, others
       which can linger for much longer.
       If the steroid can be detected for longer, drug testers can
       catch dopers who ended their steroid use a few weeks before a
       major event like the Olympics, expecting they could never be
       caught.
       “It’s very non-sexy science to find these metabolites, but it’s
       really cool what it can do, so many dopers. It’s just amazing,”
       says Marcus Ericsson, director of a WADA-accredited lab in
       Sweden.
       Research conducted in 2011 by Rodchenkov and Sobolevsky found
       six new metabolites. One referred to as M3 in their research
       proved to be the key, raising the detection window from a few
       days of last use to as much as seven weeks, Rodchenkov and
       Sobolevsky estimated.
       Rodchenkov and Sobolevsky “had excellent scientific knowledge on
       methods, on steroid metabolism, really excellent,” says Peter
       Van Eenoo, who runs a drug testing laboratory in Belgium and
       frequently met both men at conferences.
       “Grigory, I need to say, also had knowledge which was better
       than most other lab directors, if not all lab directors, on
       usage, how people were using, the doses they were using ... It
       did make some people wonder how he knew about this.”
       Turinabol, also known as dehydrochlormethyltestosterone, has not
       been manufactured for legitimate medical purposes for years but
       is widely sold on the black market without proper quality
       control. In many countries, that means it’s difficult to conduct
       scientific studies using volunteers without breaking medical
       ethics rules, so it’s hard to tell exactly how long it stays in
       the human body.
       The drug has also been linked to health problems by East German
       athletes forced to take it during the Cold War.
       Before the 2012 London Olympics, McLaren alleges Rodchenkov
       helped Russian authorities with secret testing of his own before
       their departure to ensure doped athletes would test clean later.
       His new discovery about turinabol was published too late to use
       in testing at the games, but was pioneered by a laboratory in
       Germany soon after. The new technology began to catch dozens of
       athletes, though not from the Olympics, because those samples
       had already been processed.
       However, Rodchenkov was playing a more complex game. According
       to his testimony, he had been doping Russian athletes with
       turinabol but now, as McLaren writes, “while appearing to be at
       the forefront of the development of doping detection science, he
       was secretly developing a cocktail of drugs with a very short
       detection window.”
       Rodchenkov testified earlier this year that turinabol was
       replaced in the new “Duchess” cocktail with trenbolone, a
       steroid usually used for muscle growth in farm animals. There is
       still no new test for trenbolone using long-term metabolites,
       and there have been no positive cases for it in more than 100
       IOC retest cases from 2008 or 2012.
       Rodchenkov hasn’t explained his motivations for publishing his
       research into turinabol, but Van Eenoo, the director of the
       Belgian lab, suspects an attempt to catch out Russia’s rivals.
       Many Russians have been caught but other ex-Soviet countries
       like Belarus and Kazakhstan have seen their Olympic
       weightlifting programs almost wiped out by turinabol retests.
       “If you’re really clever, you’d only do this once you’ve got
       something else and you want to hit the competition,” Van Eenoo
       said.
       Rodchenkov’s double life and his lurid testimony of steroids
       dissolved in whiskey and samples swapped in the middle of the
       night have led some to doubt the credibility of his turinabol
       research.
       “They can’t be described as those turinabol metabolites using
       this method,” says sports lawyer Artyom Patsev, who represents
       some Russians who failed IOC retests. “What could they be? Maybe
       they’re metabolites of a different steroid. Maybe they’re
       metabolites of orange juice.”
       Of several lab directors consulted by the AP, some privately
       expressed reservations about how the original research may have
       been conducted in the tainted Moscow lab, but all said its
       findings had been upheld by subsequent work elsewhere. The
       metabolite in question, they said, could only come from
       turinabol or “designer steroids” based on turinabol but so close
       to the original they would also come under the same ban. WADA
       says it’s a “validated method.”
       Rodchenkov left Russia for the U.S. before going public with his
       revelations. The Russian state’s position toward him varies.
       Some officials have attacked his mental health or claimed he is
       being paid to lie, while others, particularly in law
       enforcement, have painted him as the ringleader in a conspiracy
       to force athletes to dope.
       In Switzerland, Rodchenkov’s public research and his illicit
       practices have combined to produce the busiest year of Olympic
       drug retesting ever. More is to come after the IOC said Friday
       every Russian sample from 2012 would be examined again.
       “It has been an interesting period,” Lausanne lab director
       Kuuranne said last week of her ever-changing job handling the
       IOC’s retests. “This, I think, is the spice of any kind of
       forensic analysis. It’s quite a dynamic field.”
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