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#Post#: 6087--------------------------------------------------
Testosterone Depot
By: Road2HardCoreIron Date: May 4, 2025, 11:34 am
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Therapeutic Index
Testosterone
Testosterone Propionate
Each 2ml ampoule.:
Testosterone Propionate..........200mg / 2ml
SUBSTANCE: Testosterone Propionate USP
CONTENT: Available in: 200mg/1ml /2ml amp. / 10ml Vial
COMPOSITION :
Testerone
Testosterone Propionate inj.
The most common dosage schedule for Testosterone Propionate
(men) is to inject 50 to 100 mg, every 2nd or 3rd day. As with
the more popular esters, the total weekly dosage would be in the
range of 200-400 mg. As with all testosterone compounds, this
drug is most appropriately suited for bulking phases of
training. Here it is most often combined with other strong
agents such as Dianabol, Anadrol 50 or Deca-Duralin,
combinations that prove to be quite formidable. Propionate
however is sometimes also used with non aromatizing
anabolics/androgens during cutting or dieting phases of
training, a time when its' fast action and androgenic nature are
also appreciated. Popular stacks include a moderate dosage of
propionate with an oral anabolic like Winstrol (15-35 mg daily),
Primobolan (50-150 mg daily) or Oxandrolone (15-30 mg daily).
Provided the body fat percentage is sufficiently low, the look
of dense muscularity can be notably improved (barring any excess
estrogen buildup from the testosterone). We can further add a
non-aromatizing androgen like Trenbolone, which should have an
even more extreme effect on subcutaneous body fat and muscle
hardness. Of course with the added androgen content any related
side effects will become much more pronounced.
INDICATIONS :
Testosterone propionate is a commonly manufactured, oil-based
injectable testosterone compound. The added propionate ester
will slow the rate in which the steroid is released from the
injection site, but only for a few days. Testosterone propionate
is therefore comparatively much faster acting than other
testosterone esters such as cypionate or enanthate, and requires
a much more frequent dosing schedule. While cypionate and
enanthate are injected on a weekly basis, propionate is
generally administered (at least) every third day. Figure one
illustrates a typical release pattern after injection. As you
can see, levels peak and begin declining quickly with this ester
of testosterone.
To make Testosterone Propionate even more uncomfortable to use,
the propionate ester can be very irritating to the site of
injection. In fact, many sensitive individuals choose to stay
away from Testosterone Propionate completely, their body
reacting with a pronounced soreness and low-grade fever that may
last for a few days. Even the mild soreness that is experienced
by most users can be quite uncomfortable, especially when taking
multiple injections each week. The standard esters like
enanthate and cypionate, which are clearly easier to use, are
therefore much more popular among athletes
Those who are not bothered by frequent injections will find that
propionate is quite an effective steroid. It is of course of
powerful mass drug, capable of producing rapid gains in size and
strength. At the same time the buildup of estrogen and DHT
(dihydrotestosterone) will be pronounced, so typical
testosterone side effects are to be expected. Some do consider
Testosterone Propionate to be the mildest testosterone ester,
and the preferred form of this hormone for dieting/cutting
phases of training. Some will go so far as to say that
propionate will harden the physique. while giving the user less
water and fat retention than one typically expects to see with a
testosterone. Realistically however, this is nonsense. The ester
is removed before testosterone is active in the body, and
likewise the ester cannot alter the activity of the parent
steroid in any way, only slow its release. We can say that
propionate might be the favored testosterone among female
bodybuilders (for those who insist on testosterone use!) as
blood levels are easier to control with it compared to other
esters. Should virilization symptoms develop, one would not wish
to wait the weeks needed for testosterone concentrations to fall
after a shot of enanthate for example.
Testosterone Propionate (men) is to inject 50 to 100 mg, every
2nd or 3rd day. As with the more popular esters, the total
weekly dosage would be in the range of 200-400 mg During a
typical Testosterone Propionate cycle one will see action that
is consistent with a testosterone. Users sensitive to
gynecomastia may therefore need to addition an antiestrogen.
Those particularly troubled may find that a combination of
Nolvadex and Proviron works especially well at
preventing/halting this occurrence. Also unavoidable with a
testosterone are androgenic side effects like oily skin, acne,
increased aggression and body/facial hair growth. Those who may
have a predisposition for male pattern baldness may also find
that propionate will aggravate this condition. To help combat
this we also have the option of adding Proscar, which will
reduce the buildup of DHT in many androgen target tissues. This
will help minimize related side effects (particularly hair loss)
although it offers us no guarantees. And as with all
testosterone products, propionate will also suppress endogenous
testosterone production. The use of a testosterone stimulating
drug like HCG and/or Clomid is therefore almost a requirement in
order to avoid enduring a post-cycle crash.
Testosterone Propionate (men) is to inject 50 to 100 mg, every
2nd or 3rd day. As with the more popular esters, the total
weekly dosage would be in the range of 200-400 mg
The most common dosage schedule for Testosterone Propionate
(men) is to inject 50 to 100 mg, every 2nd or 3rd day. As with
the more popular esters, the total weekly dosage would be in the
range of 200-400 mg. As with all testosterone compounds, this
drug is most appropriately suited for bulking phases of
training. Here it is most often combined with other strong
agents such as Dianabol, Anadrol 50 or Deca-Durabolin,
combinations that prove to be quite formidable. Propionate
however is sometimes also used with non aromatizing
anabolics/androgens during cutting or dieting phases of
training, a time when its' fast action and androgenic nature are
also appreciated. Popular stacks include a moderate dosage of
propionate with an oral anabolic like Winstrol (15-35 mg daily),
Primobolan (50-150 mg daily) or Oxandrolone (15-30 mg daily).
Provided the body fat percentage is sufficiently low, the look
of dense muscularity can be notably improved (barring any excess
estrogen buildup from the testosterone). We can further add a
non-aromatizing androgen like Trenbolone, which should have an
even more extreme effect on subcutaneous body fat and muscle
hardness. Of course with the added androgen content any related
side effects will become much more pronounced.
Women who absolutely must use an injectable testosterone should
only use this preparation. The Testosterone Propionate dosage
schedule should also be more spread out for a female
bodybuilder, with injections coming every 5 to 7 days. The
dosage obviously would be lower as well, generally in the range
of 25 mg to 50 mg per injection. Androgenic activity should be
less pronounced with this schedule, giving blood levels time to
sufficiently decrease before the drug is administered again. In
order to further reduce any risks, the duration of this cycle
should not exceed 8 weeks. Should a stronger anabolic effect be
needed, a small amount of Duramin (Deca-Duralin if unavailable),
Oxandrolone or Winstrol could be added. Of course the risk of
noticing virilizing effects from these drugs may increase, even
with the addition of a mild anabolic. Since many of the
masculinizing side effects of steroid use can be irreversible,
it is very important for the female athlete to monitor the
dosage, duration and incidence of side effects very closely.
COMPOSITION:
Each Injection 100 mg. ampoule contains :
Testosterone propionate 25 mg. & Testosterone Ethan-ate 110 mg
Each Injection 250 mg. ampoule contains :
Testosterone Ethan-ate 250 mg.
MODE OF ACTION:
Testosterone Propionate : It is a highly anabolic as well as
androgenic steroid. I t is a common oil-based inject able
testosterone. The added propionate extends the activity of the
testosterone but it is still comparatively much faster acting
than other testosterone esters such as cypionate and enanthate.
Propionate is most commonly injected at least every third day to
keep blood levels steady. This drug is quite effective for
strength and muscle mass gains. Propionate is often very painful
injection.
Testosterone enanthate : It is derivative of the primary
endogenous androgen testosterone, for intra muscular
administration. In their active form, androgens have a 17-beta
hydroxy group. Esterification of the 17-beta-hydroxy group
increases the duration of action of testosterone, hydrolysis to
free testosterone occurs in vivo.
CLINICAL PHARMACOLOGY: Endogenous androgen are responsible for
the normal growth and development of the male sex organs and for
maintenance of secondary sex characteristics. These effects
include growth and maturation of prostate, seminal vesicles,
penis and scrotum, development of male hair distribution such as
beard, pubic, chest and axillary hair, laryngeal enlargement,
vocal chord thickening, alterations in body musculature and fat
distribution.
PHARMACOKINETICS:
Testosterone esters less polar than free testosterone.
Testosterone esters in oil injected intramuscularly are absorbed
slowly from the lipid phase, thus testosterone enantate can be
given at intervals of two to four weeks.
Testosterone in plasma is 98% bound to a specific testostrone
estradiol binding globulin and about 2 % is free. The free
testostrone concentrate will determine its half life.
About 90% of a dose of testosterone is excreted in the urine as
glucoronic and sulfuric acid conjugates of testosterone and its
metabolites, about 6 % of a dose is excreted in the feces,
mostly in the unconjugated form.
INDICATIONS:
MALES:
Testosterone is indicated for replacement therapy in conditions
associated with a deficiency or absence of endogenous
testosterones. Primary Hypogonadism ( Congenital or acquired ) :
Testicular failure due to cryptorchidism, bilateral torsion,
orchitis, vanishing testis syndrome or orchidectomy.
Hypogonadotropic Hypogonadism (Congenial or acquired):
Idiopathic gonadotropin or leuteinizing hormone-releasing
hormone ( LHRH ) deficiency or pituitary-hypothalmic injury from
tumors, trauma or radiation. Delayed Puberty : Testosterone may
be used to stimulate puberty in carefully selected males with
clearly delayed puberty.
FEMALES:
Metastatic mammary cancer : Testosterone may be used secondarily
in women with advancing inoperable metastatic ( skeletal )
mammary cancer who are one to five years post menopausal.
DOSAGE AND ADMINISTRATION:
Total doses above 400 mg per month are not required because of
the prolonged action of the preparation.
Male Hypogonadism: As replacement therapy i.e. For eunuchism,
the dosage is 50 to 400 mg every 2 to 4 weeks.
In Males with Delayed Puberty: Dosage is within the range of 50
to 200 mg, every 2 to 4 weeks for a limited duration ( 4 to 6
months ).
In Females: Palliation of Inoperable Mammary Cancer : A dosage
of 200-400 mg every 2 to 4 weeks is recommended.
SIDE EFFECTS:
IN MALES:
Gynecomastia and excessive frequency and duration of penile
erections, Hirsutism, Male pattern baldness, Acne, Retention of
salts & water ,Nausea, Cholestatic jaundice, Suppression of
clotting factor, Increased or decreased libido, Headache,
Anxiety and depression.
IN FEMALES:
Amenorrhoea and other menstrual irregularities, inhibition of
gonadotropic secretion and virilization, including deepening of
the voice and clitoral enlargement.
CONTRAINDICATIONS:
Androgens are contraindicated in men with carcinomas of the
breast or with known or suspected carcinomas of the prostate and
in women who are or may become pregnant.
PRECAUTIONS:
Peliosis hepatis can be fatal complication, The androgen should
be discontinued, if cholestatic hepatitis with jaundice appears.
Geriatric patients may be a the risk for the development of
prostatic hypertrophy and prostatic carcinoma.
Caution is required in patients with pre existing cardiac, renal
or hepatic disease, due to sodium and water retention properties
of androgens.
DRUG INTERACTIONS:
When administered concurrently, the following drugs may interact
with androgens :
Oral anticoagulants, Antidiabetic drugs and insulin, ACTH &
corticosteroids, oxyphenbutazone.
STORAGE:
Testosterone Inj. should be stored at room temperature.
PRESENTATION:
1 ampoule of Testosterone DEPOT INJECTION 100 mg
contains:Testosterone propionate 25 mg & Testosterone enanthate
110 mg
1 ampoule of Testosterone DEPOT INJECTION 250 mg contains:
Testosterone enanthate 250 mg
FOR INTRA MUSCULAR USE ONLY.
PACKAGING INFORMATION :
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