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#Post#: 5507--------------------------------------------------
Which is better T-3 or T-4?
By: Road2HardCoreIron Date: September 22, 2024, 12:21 pm
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Should I take T3 only for my hypothyroidism?
Should I take T3 only for my hypothyroidism?
July 13, 2018
The thyroid gland makes 2 hormones, T4 and T3. T3 is the active
hormone, and the body converts T4 to T3 by deiodinases. Most
patients with hypothyroidism are treated with T4, and their
doctors assume that it gets converted to T3 physiologically. For
many patients this happens, and many patients do well on
T4-alone treatment. However, some patients do not do this
conversion well, and those patients would do better on a T4/T3
combination. The T4/T3 can be either given as a levothyroxine
preparation such as Synthroid, Levoxyl, or Unithroid, plus T3.
The brand name of T3 is called Cytomel and the generic is called
liothyronine. Another way to get both T4 and T3 is to take
desiccated thyroid, which comes from pig thyroid and has both T4
and T3 in it. Desiccated thyroid also has other ingredients in
the thyroid that are missing in synthetics.
Dr. Friedman frequently uses different combinations of thyroid
medicine, including T4/T3 combinations and desiccated thyroid.
However, some more alternative doctors are prescribing only T3
to patients.
Dr. Friedman recommends against this for several reasons. First
of all, several studies have shown that T4 gets into the brain
much better than T3 does, and once it’s in the brain the T4 can
get converted to T3. Therefore, in patients only on T3, the
level of thyroid hormone in the brain might be quite low.
Additional, T4 has a long half-life and acts as a reservoir,
while T3 has a short half-life and needs to be given several
times a day if it is not in combination with T4. Dr. Friedman
also thinks it is unphysiological to have a very low T4 level,
which is what happens if someone is only taking T3.
Because the thyroid converts T4 to T3 and not the other way
around, a person with severe hypothyroidism and only on a T3
replacement will have a very low T4 level. If someone was
misdiagnosed and really did not have hypothyroidism or has very
mild hypothyroidism, the T4 could still be detectable (or even
normal) when on only a T3 combination.
Dr. Friedman has recently posted an article about using reverse
T3 and does find it useful in some patients. Some alternative
doctors are very concerned with keeping the reverse T3 quite low
and sometimes use only T3 to lower it. Dr. Friedman does not
find this approach to be valid, as with careful monitoring of
the reverse T3, patients could be on either a T4 plus T3
combination or desiccated thyroid and still achieve good free T4
and free T3 levels without having a high reverse T3.
If you are hypothyroid and want to take advantage of Dr.
Friedman’s expertise in this area, please do not hesitate to
make an appointment or visit his website at
goodhormonehealth.com.
#Post#: 5512--------------------------------------------------
Re: Which is better T-3 or T-4?
By: Genetic Freak Date: September 23, 2024, 1:57 pm
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I had a client with really high rT3. I kind of suspected it and
had him get labs pulled and specifically had him get his rT3
checked. In a normal thyroid panel it looks like his thyroid was
functioning normally, even closer to hyperthyroidism. However,
once rT3 was checked we found that nearly all of his T4 was
being converted to rT3 and not T3. Treated with T4 alone is
asinine, as it will not do anything to bring down rT3. We tried
a combination T3/T4 (25/100) and it didn't put a dent in it.
Increase his T3 to 45 mcg (15 mcg 3x a day) and it still did not
come down much. He had to go all the way to 60 mcg (20 mcg 3x a
day) to get his rT3 and T3 back into the normal range.
This guy has been all over the place when it comes to hormones.
On 30 mg a test a day he had a total test of 829, which is
garbage and estrogen of 220, which is complete garbage. Said he
felt no side effects from the high estrogen... However, as he
leans down, I can see some gyno. I think he had it before he
came to me, as he was running unsupervised cycles that his gym
bros told him to do before, test and d-bol. He was running 600
mg of test and 50 mg of d-bol with no AI or SERM. If a TRT dose
had his estrogen at 220, I couldn't even imagine what 3x a TRT
dose and d-bol would look like.
#Post#: 5513--------------------------------------------------
Re: Which is better T-3 or T-4?
By: Road2HardCoreIron Date: September 24, 2024, 9:42 am
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What was his levels on 600 mg of test? I've learned Every one
is different Think most of us know. Until we work with
different clients.
FYI I've learned most of these guys on boards do not check any
levels and Def don't believe in Anti estrogens. Then they
complain how stuff ain't working. when I get their labs and add
what they need. Their, like I'm sorry. SMH. I'm thinking I'm
sorry you didn't listen. I warned you.
Since I've been on boards. Most do not no what Ant-estrogen is.
They just want Test and Tren. Some think they can't get a
woody because test is not real. I have to tell them you're
cashing. All these years. You're getting older. Your body is
not going to keep helping you out. The conversion rate is
winning. (Only the Boards) Do I have this issue. Never with
personal people or those in the game.
Now most 70%. Get Anti-estrogens. Where the hell do these guys
learn this stuff at?????
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