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Letrozole The Strongest Anti-Estrogen there is
By: Road2HardCoreIron Date: May 25, 2018, 6:28 pm
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Letrozole Doubles Mens Testosterone Levels
Letrozole Doubles Mens Testosterone Levels
Blog Entry #48
By Admin – Steroidal.com
Letrozole, or also commonly referred to as Femera, is an
anti-estrogen. To be more precise it’s actually an aromatase
inhibitor (AI) and lowers estrogen levels by binding to the
aromatase enzyme. Estrogen is produced in men mainly by the skin
and adipose tissue, but also by the adrenals, liver, mammary
glands, hair and in the male gonads. Estrogen levels are
important in men and are used for a variety of functions in the
body. These include, bone density, lipid metabolism, growth and
sexual maturation. Unfortuneatly, its not all good and when
estrogen is left to climb side effects can arise some of these
are; water retention, gynecomastia, acne, cholesterol problems,
cardiovascular issues, loss of sex drive, energy, prostate
issues, cardiovascular problems, cancers and aggression or mood
swings. These side effects can be apparent during puberty, but
also when testosterone based anabolic steroids are used as they
can aromatase and push estrogen up. Which is why AIs are used to
ward off these nasty side effects, some permanent. AI use has
risen in recent years because these side effects are more
understood and AIs have been more widely available now often
sold for “research”.
A compound that blocks estrogen, much like a selective estrogen
receptor modulator (SERM), or lowers circulating estrogen levels
has the ability to raise natural levels of testosterone. These
work by different mechanisms, but essentially anything
anti-estrogenic can raise total testosterone in healthy men. A
SERM does this by blocking the estrogen receptor in the
hypothalamus and an AIs mode of action is changing the
androgen:estrogen ratio. The human body is a fantastic and
clever biological machine, and when it senses a low estrogen
level, it compensates by increasing testosterone output to
balance testosterone and estrogen. But how much can it raise
natural testosterone levels?
In 2010 Urologists at the University of Mersin in Turkey,
conducted a study on 27 infertile men [1]. The men were given
the 2.5mg for six months, half of which suffered from Azospermia
(no sperm).
The figure below shows that the men given 2.5mg every day of
Letro had doubled their testosterone levels in six months.
Estrogen levels also fell 45%. In another study done in Canada
in 2009, Letro again
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