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       #Post#: 3004--------------------------------------------------
       Chinese VS American Growth
       By: Road2HardCoreIron Date: March 9, 2023, 10:38 pm
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       Is there a difference between western (big pharma) made growth
       hormone and growth hormone made in China?
       Question:
       Is there a difference between western (big pharma) made growth
       hormone and growth hormone made in China?
       Answer:
       Other than 90/10 price difference ratio, both are identical.
       Western big pharma corporations use exactly the same production
       procedure (recombinant DNA technology) and equipment as Chinese
       labs. Chinese laws regarding GMP and safety of medicine related
       products are stricter than those in the west.
       The identification, purification and later synthesis of growth
       hormone was first accomplished by a Chinese pioneer Choh Hao Li.
       Nowadays almost everything used in the west is made in China (or
       Asia at least) - both the high quality products as well as the
       low quality copies.
       Human growth hormone (somatropin) is a large and fragile, 191
       amino acid sequence molecule with a molecular weight of
       approximately 22,000 Daltons. There is no room for differences.
       The substance is either somatropin or it is not. If the molecule
       gets distorted even a little, it will no longer bind to growth
       hormone receptors.
       The reason Chinese goods are often seen as inferior is the vast
       availability of cheap copies of everything (clothes,
       electronics, etc..) which visually appear the same as original
       but are composed of cheaper, inferior material and are thus
       lower quality and less durable. With production of somatropin
       this is not possible. The necessary equipment to even create it,
       comes at a multi million dollar price, so steroid "bathtub" labs
       are not capable of making it.
       The only somatropin manufacturing method which is still used
       today (both in the west and asia) is the recombinant DNA
       technology, where E. Coli bacteria are genetically modified to
       secrete human growth hormone, which is then isolated and can be
       either lyophilized (freeze dried) or stored in the liquid form.
       While somatropin is in the liquid form, it is very sensitive to
       temperature and shaking. If not refrigerated and handled with
       care the molecules easily get destroyed. While in freeze dried
       state, somatropin is not sensitive to shaking and it can survive
       temperatures up to 45 degrees celsius (113 fahrenheit). Because
       of this, it is only transported in lyophilized form.
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