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       #Post#: 2403--------------------------------------------------
       Reading Bloodwork Before and While on Cycle
       By: Road2HardCoreIron Date: January 18, 2023, 5:08 pm
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       Anabolics and Understanding Blood Tests
       Anabolics and Understanding Blood Tests, what to look for, and
       how to do it.
       WHAT AM I LOOKING FOR IN A BLOOD WORK?
       Blood Work Categories
       Hormone
       Lipids (Cardiovascular)
       Liver Function
       Muscle Enzyme
       Blood
       Kidney
       Electrolytes, Minerals, and Glucose
       Prostate
       Anabolics and Understanding Blood Tests, what to look for, and
       how to do it.
       When people ask me about starting steroids/cycling, I always
       tell them to get blood work done.
       Unfortunately this is met with a lot of resistance, and some
       people just don’t see the value in doing this.
       I promised a blog response, and I’ll give it to you here.
       This is what I’ve learned over the years through trial and
       error, good individual knowledge, and reading…a ton of reading.
       Most people understand that steroids come with risks. This is
       why its so important to get a base, or starting point of where
       you are BEFORE you begin. Then you can find out if you have
       healthy blood levels, see where they are at your starting point,
       and see if you have any warning signs BEFORE you begin so you
       can address them correctly.
       Then we have something to compare it to when we do our later
       comparison. It is far easier to see what the cycle is doing to
       your body when re testing blood work during the cycle.
       The last Blood work will be done post cycle, again to test and
       monitor health and regeneration of normal blood levels.
       ******Some people are using Roid test kits, See out new Video
       Series HERE
       testosterone-roidtest-product
       That is a great option to test a Lab (UGL) out of the gate. That
       being said, I have always gone on feel and blood work.  I go on
       the reputation of a brand, then I monitor my results and my
       bloodwork. You will be able to see differentials in your blood
       results and monitor that instead of trying to test every vial.
       What I do think is that some of the vials may be / are “off
       does” or incorrectly dosed. Some may be higher, some may be
       lower. Im personally not going to test every vial. Once Im using
       a brand (lab) for some period of time Im certainly not going to
       test everything. I just continue to go off my blood test results
       and how Im feeling, my progress etc. If I feel like the brand
       (lab) is not performing I switch. It’s that simple.*******
       
       WHAT AM I LOOKING FOR IN A BLOOD WORK?
       testosterone-lab-test
       
       PRE CYCLE
       This is where we start first to make sure there are no pre
       existing health conditions that will make the matter worse by
       use of substances. This also gives us a base to compare our on
       cycle / off cycle results.
       Below Is THE MINIMUM Results We Will Want To Check And See
       Results For:
       Hormone (Steroid
       Lipids (Standard Full Set)
       Full Liver Panel
       Blood
       Kidney
       Electrolytes, Minerals, and Glucose
       Prostate
       
       ON CYCLE
       This testing is usually conducted 3 to 4 weeks after the steroid
       cycle has started.
       It is with these tests that will most reflect the changes made
       by the steroid cycle.
       It is important to note any adverse side effects and take into
       account that if used over time how that will impact overall
       health.
       Below Is THE MINIMUM Results We Will Want To Check And See
       Results For:
       Lipids (Standard Full Set)
       Full Liver Panel (if taking hepatotoxic steroids)
       Blood
       Kidney
       Electrolytes, Minerals, and Glucose
       
       POST CYCLE
       The Post Cycle Test will determine is your male steroid hormone
       has returned to pre cycle levels. There will always be some
       variation on this test and an exact match will be almost
       impossible. It is also recommended to look at the LH and FSH
       pituitary in the case of the blood coming back low, it is easier
       to determine the cause.  High LH/FSH and low testosterone
       (primary hypogonadism) may simply indicate that your testicles
       have not yet fully restored their mass. Alternatively, low
       LH/FSH can indicate secondary hypogonadism, which is often cause
       to initiate corrective therapy with an endocrinologist. Other
       general indicators of health are also conducted here including
       lipids, liver, blood, kidney, electrolytes, minerals, glucose,
       and prostate.
       Below Is THE MINIMUM Results We Will Want To Check And See
       Results For:
       Hormone (Steroid, LH/FSH)
       Lipids (Standard Full Set)
       Full Liver Panel (if taking hepatotoxic steroids)
       Blood
       Electrolytes, Minerals, and Glucose
       Prostate
       
       
       CREDIT** –  Below is an abbreviated version of William
       Llewellyns ANABOLICS 9th ed.
       There are many versions of this book available.  I highly
       recommend you picking yourself up a copy. If you are dedicated
       enough to start using Anabolics, then you should be dedicated
       enough to read a book about what you are about to do.
       
       
       Blood Work Categories
       Hormone
       hand with pen drawing the chemical formula of testosterone
       
       Steroid (male)
       Test Name
       Testosterone, Total
       Reference Range – 241 – 827  ng/dl
       Testosterone, Free
       Reference Range – 8.7 – 25.1  pg/ml
       Estradiol
       Reference Range – 10-53  pg/ml
       
       LH/FSH Panel (male)
       Test Name
       LH
       Reference Range – 2.5 – 9.8    IU/L
       FSH
       Reference Range – 1.2 – 5.0    IU/L
       
       Steroid (male)
       Test Name
       Testosterone, Total
       Reference Range – 241 – 827  ng/dl
       Testosterone, Free
       Reference Range – 8.7 – 25.1  pg/ml
       Estradiol
       Reference Range – 10-53  pg/ml
       
       Steroid: This testing will look at both total and free
       testosterone. The former measurement is used by physicians to
       identify the androgen level and determine if there is a need for
       therapy. The latter measure actually represents the fraction of
       bioavailable (immediately active) testosterone in the body, and
       is consequently regarded as more important for assessing the
       present state of androgenicity. Estradiol is the principle
       active form of estrogen in the body, and has roles both in
       potential side effects (gynecomastia, water/fat retention) and
       hormone balance. This is the estrogen marker most often
       recommended during hormone profiling.
       LH/FSH Panel: Luteinizing hormone (LH) and follicle stimulating
       hormone (FSH) are responsible for stimulating testosterone
       production and spermatogenesis in the testes. These measures are
       most relevant when evaluating the cause and potential treatment
       options for hypogonadism, not the short-term health impact of
       anabolic-steroid use. The short-term suppression of LH/FSH is
       expected with anabolic/androgenic steroid administration.
       Thyroid: It is regarded as important to get a baseline measure
       of thyroid activity, usually once per year. Follow up tests
       during and after steroid use may be an expense some view as
       unnecessary. Anabolic/androgenic steroid use is unlikely to
       permanently affect thyroid function, but may slightly elevate
       thyroid levels during therapy. A misdiagnosis of hyperthyroidism
       (overactive thyroid) is sometimes made in light of these
       elevated numbers. The effect of anabolic/androgenic steroid use
       on thyroid levels should be taken into account before treatment
       for hyperthyroid is ordered.
       
       Lipids (Cardiovascular)
       Lipids Image2
       
       Anabolic/androgenic steroids can have strong adverse effects on
       lipids. The abuse of anabolic/androgenic steroids (particularly
       long-term abuse) can, likewise, increase the risk for developing
       cardiovascular disease as assessed by these variables.
       Mitigating these risks with the careful examination of the lipid
       profile is regarded as one of the most fundamental of all
       steroid-related blood tests. While far from comprehensive with
       regard to assessing total heart disease risk, a full panel
       examining the variables below (and comparing them to your
       baseline values) can provide a good snapshot of the
       cardiovascular impact of anabolic/androgenic steroid use. It is
       important to measure your blood lipids only after 12 hours of
       fasting, as food intake can skew the outcome of some measures
       (particularly triglycerides).
       
       Standard Full Set
       Test Name                                          Reference
       Range
       Triglycerides
       Reference Range – 0 – 149  mg/dl
       Cholesterol, Total
       Reference Range – 100 – 199  mg/dl
       HDL Cholesterol
       Reference Range – >40  mg/dl
       VLDL Cholesterol
       Reference Range – 5 – 40  mg/dl
       LDL Cholesterol
       Reference Range – <100  mg/dl
       LDL/HDL Ratio
       Reference Range – <3.6  mg/dl
       
       LDL/HDL Ratio Risk Assessment
       
       1/2 Average Risk
       Men  1.0                          Women  1.5
       Average Risk
       Men  3.6                          Women  3.2
       2x Average Risk
       Men  6.3                          Women  5.0
       3x Average Risk
       Men  8.0                          Women  6.1
       
       Additional Testing
       Test Name
       C-reactive Protein
       Reference Range – <5   mg/dl
       Homocysteine (0-30 years)
       Reference Range – 4.6 – 8.1   umol/L
       Men (30-59)
       Reference Range – 6.3 – 11.2  umol/L
       Women (30-59)
       Reference Range – 4.5 – 7.9  umol/L
       >59 years
       Reference Range –  5.8 – 11.9  umol/L
       
       Apo Ratio Testing
       Apolipoproteins
       apoB/apoA-1 Ratio
       Reference Range – Men <.9                             Women  <.8
       Apo Ratio Risk Assessment
       Low Risk
       Men <.7                            Women <.6
       Average Risk
       Men .7 – .9                             Women .6 – .8
       High Risk
       Men >.9                             Women >.8
       
       Standard Full Set: This is a standard full lipid panel
       examination. Ideally, all values should be kept within the
       normal ranges at all times during steroid therapy. Note that the
       LDL/HDL ratio is regarded as the most important measure of the
       serum lipid tests, as it reflects the ongoing balance between
       plaque deposition (LDL) and removal (HDL) in the arteries. The
       LDL/HDL ratio is used to more closely assess heart disease risk
       in individuals that have elevated LDL or total cholesterol
       levels.
       Additional Testing: (-reactive protein and homocysteine are two
       additional markers that are important to examining
       cardiovascular health. (-reactive protein is a key indicator of
       inflammation in the body, and homocysteine is involved in blood
       clotting and LDL cholesterol oxidation. It is also advisable to
       include these two variables in your cardiovascular testing
       schedule.
       Apo Ratio: Apolipoprotein ratio testing is also recommended.
       Although not commonly used in general medical practice,
       apolipoprotein testing is increasingly regarded as a more
       accurate predictor of cardiovascular disease risk than
       cholesterol testing. Apolipoprotein B (apoB) is found in all LDL
       particles, and is responsible for attaching these lipoproteins
       to the artery walls. Apolipoprotein A-I (apoA-1) is found mainly
       in HDL particles, and is responsible for initiating beneficial
       reverse cholesterol transport. ApoA-1 enables the HDL particles
       to pull cholesterol from the artery walls and transport them
       back to the liver. The ratio of apoB to apoA-I, therefore,
       appears to reflect a much truer measure of the balance of
       potentially atherogenic and antiatherogenic particles in the
       blood. A ratio above .9 is generally regarded as indicative of
       increased cardiovascular disease risk. Lower ratios reflect
       reduced cardiovascular disease risk assessments.
       
       Liver Function
       highlighted-liver-in-human-body
       
       Test Name
       Albumin
       Reference Range – 3. 5 – 5.5   g/dL
       Globulin
       Reference Range – 1.5 – 4.5   g/dL
       Total Protein
       Reference Range – 6.0 – 8.5   g/dL
       Bilirubin
       Reference Range – 0.1 – 1.2   mg/dL
       GGT (Gamma GT)
       Reference Range – 50          IU/L
       ALP (Alkaline Phosphatase)
       Reference Range – 25 – 100  IU/L
       AST (SGOT)
       Reference Range – 0 – 40       IU/L
       ALT (SGPT)
       Reference Range – 0 – 55       IU/L
       
       A full liver panel is important to assessing hepatic strain. The
       two markers of liver stress most commonly elevated in abusers of
       anabolic/androgenic steroids are the enzymes alanine
       aminotransferase (ALT) and aspartate aminotransferase (AST). ALT
       and AST are necessary to amino acid metabolism in the liver, and
       will leak into the bloodstream as the liver becomes inflamed or
       damaged.
       These two enzymes are generally regarded as important indicators
       of early steroid-induced liver toxicity. There have been cases
       in which substantial liver damage has occurred without
       substantial elevations in ALT and AST, however, so a more
       detailed examination of liver enzyme values is always advised.
       Alkaline phosphatase (ALP) and gamma-glutamyltranspeptidase
       (GGT) are known as cholestatic liver enzymes, which mean they
       diminish or stop the flow of bile (a greenish fluid that aids
       digestion and is produced in the liver).
       ALP and GGT are important markers of liver health during steroid
       use, and should be included in regular blood testing. Elevations
       in ALP and GGT can indicate bile duct obstruction (intrahepatic
       cholestasis), which refers to a condition where the liver can no
       longer properly transport and metabolize bile.
       Intrahepatic cholestasis is a potentially very serious
       manifestation of steroid-induced liver toxicity, so elevations
       in ALP and GGl should not be disregarded. Mild elevations in ALT
       and AST may be caused by muscle damage (exercise) and not
       steroid-induced liver toxicity.
       A comparison to baseline levels will be important in determining
       the cause. If the only factor that has changed is the addition
       of a hepatotoxic anabolic steroid (training is otherwise
       steady), the drug is likely to blame. It is important to
       remember that ALP and GGT are not always elevated with early
       liver strain. Therefore, the elevation of any hepatic markers
       above the reference range (even if only ALT and AST) can
       indicate liver toxicity, and should be cause to discontinue the
       offending steroids and reassess risk.
       
       Muscle Enzyme
       Muscle Enzyme
       
       Test Name
       Creatine Kinase
       Reference Range – 38-174 u/L
       
       The creatine kinase (CK) enzyme is used as a marker of muscle
       breakdown, kidney damage, and heart damage. High levels usually
       indicate heart attack or other organ trauma. This enzyme can
       also become elevated with exercise that breaks down muscle
       tissue, especially intense endurance or resistance training.
       Elevated CK levels caused by high intensity training are often
       mistaken for organ damage. It is important to further examine
       other markers of kidney and heart heath before such a
       determination is made. Note that creatine kinase levels may also
       be useful in determining if liver strain or heavy training is
       the cause of mild elevations in liver enzymes ALT and AST.
       Slight increases in ALT and AST caused by muscle damage will
       usually coincide with elevated CK and normal ALP and GGT levels.
       
       Blood
       Blood-test
       
       Test Name
       WBC
       Reference Range – 4 – 11    –  K/MCL
       RBC
       Reference Range – 81 – 103  –  FL
       Platelet Count
       Reference Range – 130 – 400   –   K/MCL
       Hemoglobin
       Reference Range – 13 – 17   –   g/dL
       Hematocrit
       Reference Range –  40.7 – 50.3 (men)  –   %
       Reference Range – 40.7 – 50.3 (women)  –  %
       
       A full blood count is one of the most commonly run blood tests,
       and can give you a good snapshot of overall health in many
       regards. A full blood cell test will give you a measure of white
       cell count (responsible for fighting infection), platelet count
       (vital to blood clotting and healing), and red blood cell count
       (responsible for carrying oxygen). Red and white cell counts
       will be further subdivided into various individual measurements,
       often referred to as a differential cell count.  Hemoglobin is
       the specific carrier of gases in red cells, and hematocrit is a
       measure of the percentage of red blood cells in the total blood
       volume. Due to their effects on erythropoiesis, anabolic
       steroids tend to increase red blood cell count, hematocrit, and
       hemoglobin concentrations. While this may increase
       oxygen-carrying (aerobic) capacity, as the concentration of red
       blood cells increases so does the thickness of the blood.
       Elevated hematocrit can increase the risk of heart attack or
       stroke.
       
       Kidney
       kidney-damage graphic
       Test Name
       Uric acid
       Reference Range – 3.0 – 7.0   – mg/dL
       Creatinine
       Reference Range – .5 – 1.5  –   mg/dL
       BUN
       Reference Range –  5 – 26  –  mg/dL
       BUN/creatinine
       Reference Range – 8 – 27
       
       This panel of tests looks at three primary waste products
       filtered and excreted through the kidneys, urea, uric acid, and
       I creatinine. Problems here can indicate serious underlying
       problems with kidney function. Note that Blood Urea Nitrogen :
       (BUN) is often elevated with excess protein consumption, and is
       used by many physicians as an indicator that too much , protein
       is being consumed for optimal metabolism. The high consumption
       of meat or creatine supplementation can also elevate creatinine
       levels, diminishing the value of blood creatinine testing as a
       marker of kidney health. Electrolyte, mineral, and fasting
       glucose testing is important to further assessing kidney health,
       and is advised in addition to the above kidney markers. A quick
       urine screen for pH, specific gravity, and the presence of
       sugar, blood, and ketones is also available at most physicians’
       offices, and is generally advised alongside blood work when
       possible.
       
       
       Electrolytes, Minerals, and Glucose
       Electrolytes
       
       Test Name
       Sodium
       Reference Range – 136 – 146  –  mEq/L
       Potassium
       Reference Range – 3.6 – 5.2   –   mEq/L
       Chloride
       Reference Range – 98 – 109   –  mEq/L
       Bicarbonate (carbon dioxide)
       Reference Range – 21 – 30   –   mEq/L
       Phosphorous
       Reference Range – 2.5 – 4.5    –   mg/dL
       Calcium
       Reference Range – 8.5 – 10.5   –   mg/dL
       Iron
       Reference Range – 35 – 185   –   mcg/dL
       Glucose (fasting)
       Reference Range – 70 – 110   –  mg/dL
       
       Electrolyte levels are examined to help detect problems with the
       fluid and electrolyte balance. Abnormal values may reflect
       something as small as sodium or potassium deficiency, or a more
       serious condition such as kidney disease. A variety of other
       health issues may also become apparent by looking at both
       electrolyte and mineral levels, giving them somewhat broad
       prognostic value. Fasting glucose is also examined to determine
       if the individual may be hypoglycemic (low blood sugar) or
       hyperglycemic (high blood sugar). Problems with fasting glucose
       may reflect potentially serious health condition including
       metabolic syndrome, diabetes, pancreati disease, liver disease,
       kidney failure, or acute stress.
       
       
       
       Prostate
       prostate_gland
       
       Test Name
       PSA,serum
       Reference Range – 0.0 – 4.0 –   ng/mL
       
       Prostate-specific antigen (PSA) is a protein produced by cells
       in the prostate gland. Its levels can become elevated in cases
       of benign prostate hypertrophy or prostate cancer. While it
       remains unknown if elevating the level of androgens in the body
       with anabolic/androgenic steroids can increase the risk of
       prostate cancer, it is known that I this disease can be
       progressed by elevated hormone (androgen and estrogen) levels.
       The PSA test is regarded as an important diagnostic tool for
       screening individual prostate cancer risk. If PSA levels are
       elevated, most will advise against using anabolic/androgenic
       steroids.
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