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       #Post#: 116--------------------------------------------------
       Growth Hormone
       By: Road2HardCoreIron Date: April 29, 2018, 6:42 pm
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       Medical Definition of Growth hormone
       Growth hormone: A hormone made in the pituitary gland that
       stimulates the release of another hormone called somatomedin by
       the liver, thereby causing growth. Also known as somatotropin.
       Growth hormone is produced by the anterior pituitary gland, the
       front section of the gland, and is a polypeptide that consists
       of 191 amino acids. Growth hormone is given to children with
       pituitary dwarfism (short stature due to underfunction of the
       anterior pituitary) to help them grow. Excessive growth hormone
       production in children can lead to gigantism, and in adults it
       can lead to acromegaly.
       The US Food and Drug Administration (FDA) in 2003 approved a new
       use for Humatrope, a biosynthesized brand of human growth
       hormone, for the long-term treatment of children with idiopathic
       (of unknown origin) short stature, also called non-growth
       hormone deficient short stature. "Short stature" has been
       defined by the American Association of Clinical Endocrinologists
       and the Growth Hormone Research Society as height more than 2
       standard deviations (SD) below the mean for age and sex. This
       corresponds to the shortest 2.3% of children. This new
       indication restricts therapy to children who are even shorter,
       specifically more than 2.25 SD below the mean for age and sex,
       or the shortest 1.2% of children. For example, for 10-year old
       boys and girls, this would correspond to heights of less than 4'
       1" inch. This would further correspond to heights of less than
       5' 3" and 4' 11" in adult men and women, respectively. In
       clinical studies, the drug added several inches to the
       children's eventual height.
       
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