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#Post#: 50--------------------------------------------------
‘Striking’ coronavirus mutations found within one family cluster
, Chinese scientists
By: mixin Date: February 4, 2020, 12:38 pm
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Stephen Chen in Beijing
Published: 11:30pm, 3 Feb, 2020
Researchers studying a cluster of infections within a family in
the southern province of Guangdong said the genes of the virus
went through some significant changes as it spread within the
family.
Two nonsynonymous changes took place in the viral strains
isolated from the family, according to a new study by Professor
Cui Jie and colleagues at the Institut Pasteur of Shanghai.
Cui’s team also detected a total of 17 nonsynonymous mutations
from cases around the country between December 30 and late
January, they wrote.
Sars, or severe acute respiratory syndrome, mutated at the speed
of 1 to 3 changes per thousand “sites” each year, according to
previous studies.
Shi said that scientists still did not know the mutation speed
of the new coronavirus because “most of the available [viral
gene] sequences are not complete. They come in fragments.”
But on Saturday, the Zhejiang Provincial Centre for Disease
Control and Prevention (Zhejiang CDC) said it was teaming up
with tech giant Alibaba, which owns the South China Morning
Post, to develop a new method of genome analysis using
artificial intelligence to study the virus from patient samples.
The Zhejiang CDC said the new technology was expected to cut the
sequencing time from several hours to about 30 minutes, allowing
scientists to track mutations quicker and more precisely.
It is not clear yet what the mutations mean for patients. Qiu
Haibo, a member of the national expert panel advising the
government on the fight against the virus, said on Sunday that
so far there was no evidence that mutations could cause
“repeated infections”.
More at the link
HTML https://www.scmp.com/news/china/science/article/3048772/striking-coronavirus-mutations-found-within-one-family-cluster
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