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#Post#: 27--------------------------------------------------
how long does the protection last
By: gsgs Date: January 31, 2020, 12:38 pm
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Little is known about the memory B-cell responses against
MERS-CoV, apart from a recent study which demonstrated the
persistence of anti-MERS-CoV antibodies in MERS survivors up to
34 months (Payne et al., 2016). On the other hand, antibody
responses against another closely related coronavirus, SARS-CoV,
were not persistent, whereby a 6-year follow-up study did not
detect memory B-cell responses in SARS survivors (Tang et al.,
2011). It is likely that some of the B-cells differentiate into
MERS-CoV-specific memory B-cells following infection or
vaccination, but the longevity and protective efficacy of these
memory B-cells against MERS-CoV infection or re-challenge remain
unresolved questions (Du et al., 2016b; Perlman and Vijay,
2016).
HTML https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688523/
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