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   DIR Return to: TYSABRI (natalizumab)
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       #Post#: 353--------------------------------------------------
       462 PML cases as of 5/14--Tysabri considered safe beyond 2-3
       years
   DIR By: agate
       Date: June 12, 2014, 6:33 pm
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       An article in  Medscape Medical News, June 12, 2014,
       Natalizumab Continued Past 24 Months Safely in MS
  HTML http://www.medscape.com/viewarticle/826643#1,
       reports:
       --- Quote ---
       > Between 2005 and May 2014, among 125,800 patients with MS
       treated in the postmarketing setting, 462 cases of PML have been
       reported, of which 23% were fatal, for an incidence of 3.6
       cases/1000 treated. The highest prevalence has been in patients
       receiving natalizumab for 2 to 3 years.
       --- End Quote ---
       The unofficial chefarztfrau Website lists 464 cases as of May 7.
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