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#Post#: 2712--------------------------------------------------
Ocrelizumab and liver injury research information (PubMed)
DIR By: agate
Date: November 4, 2019, 6:43 pm
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The Overview section of the report on Ocrevus that is part of a
larger report entitled LiverTox: Clinical and Research
Information on Drug-Induced Liver Injury, issued by the National
Institute of Diabetes and Digestive and Kidney Diseases. This
section was last updated in July 2018.
HTML https://www.ncbi.nlm.nih.gov/books/NBK548145/#Ocrelizumab.OVERVIEW
The "likelihood score" for Ocrevus is E*, which is defined as:
--- Quote ---
> Category E*. The drug is suspected to be capable of causing
liver injury or idiosyncratic acute liver injury but there have
been no convincing cases in the medical literature. In some
situations cases of acute liver injury have been reported to
regulatory agencies or mentioned in large clinical studies of
the drug, but the specifics and details supportive of causality
assessment are not available. The agent is unproven, but
suspected to cause liver injury.
--- End Quote ---
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