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#Post#: 2002--------------------------------------------------
Zinbryta (daclizumab) pulled from market due to safety concerns
By: agate Date: March 2, 2018, 3:46 pm
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Zinbryta is being taken off the market, according to MedPage
Today (March 2, 2018):
HTML https://www.medpagetoday.com/neurology/multiplesclerosis/71501?xid=NL_breakingnews_2018-03-02&eun=g378374d0r
#Post#: 2016--------------------------------------------------
(Lancet editorial) End of the road for daclizumab in MS
By: agate Date: March 16, 2018, 4:36 pm
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[font=Verdana]An editorial in The Lancet (March 17, 2018) sums
up the situation with Zinbryta (daclizumab), which has been
taken off the market due to safety concerns:[/font]
HTML http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30565-8/fulltext?{$trackingTag}
#Post#: 2019--------------------------------------------------
FDA announcement about Zinbryta
By: agate Date: March 20, 2018, 8:28 pm
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The FDA notification about Zinbryta, which will be available
until April 30:
HTML https://www.fda.gov/Drugs/DrugSafety/ucm600999.htm
#Post#: 2092--------------------------------------------------
European EMA confirms severe risks associated w/MS drug Zinbryta
By: agate Date: May 23, 2018, 6:27 pm
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More on this in Multiple Sclerosis News Today, May 23,
2018--"European EMA Confirms Severe Risks Associated with MS
Drug Zinbryta":
HTML https://multiplesclerosisnewstoday.com/2018/05/23/ema-confirms-serious-risks-ms-medicine-zinbryta/?utm_source=Multiple+Sclerosis&utm_campaign=4334878b10-RSS_US_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_b5fb7a3dae-4334878b10-71286581
#Post#: 2151--------------------------------------------------
(Abst.) DRESS syndrome and daclizumab failure--were dangerous si
gns missed in clinical trials?
By: agate Date: July 18, 2018, 3:19 pm
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More on the failure of Zinbryta--from PubMed, July 18,
2018--DRESS syndrome and daclizumab failure--Were potentially
dangerous signs missed in clinical trials?":
HTML https://www.ncbi.nlm.nih.gov/pubmed/30013311
DRESS syndrome = drug reaction with eosinophilia and systemic
symptoms
This case history (see link below) goes into more detail about
DRESS syndrome--appearing in Neurology (September 1, 2018) under
the title "Drug reaction with eosinophilia after daclizumab
therapy in MS":
HTML http://nn.neurology.org/content/5/5/e479
#Post#: 2172--------------------------------------------------
(Abst.) Case of immune-mediated encephalitis related to daclizum
ab therapy
By: agate Date: August 4, 2018, 11:00 am
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From PubMed (August 4, 2018). The same issue of Multiple
Sclerosis Journal, which is where the article appears, includes
an article entitled "Immune-mediated encephalitis with
daclizumab: The final nail." The article below is entitled "A
case of immune-mediated encephalitis related to daclizumab
therapy."
HTML https://www.ncbi.nlm.nih.gov/pubmed/30073905
#Post#: 2354--------------------------------------------------
(Abst.) Severe meningo-encephalitis after daclizumab therapy for
MS
By: agate Date: January 22, 2019, 1:48 am
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The study concerns 7 patients, 2 of whom died. From Multiple
Sclerosis Journal (January 19, 2019)--"Severe
meningo-/encephalitis after daclizumab therapy for multiple
sclerosis."
HTML https://journals.sagepub.com/doi/abs/10.1177/1352458518819098
#Post#: 2664--------------------------------------------------
Daclizumab-induced encephalitis in MS
By: agate Date: September 26, 2019, 12:39 am
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Editorial in Multiple Sclerosis Journal (September 24,
2019)--"Daclizumab-induced encephalitis in multiple sclerosis":
HTML https://journals.sagepub.com/doi/full/10.1177/1352458519845079
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