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#Post#: 118--------------------------------------------------
Controlled Dual Release of Functional Molecules
By: SSamani Date: April 20, 2015, 2:23 pm
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[center]Triaxial Electrospun Nanofiber Membranes for Controlled
Dual Release of Functional Molecules
Daewoo Han and Andrew J. Steckl
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ABSTRACT
A novel dual drug delivery system is presented using triaxial
structured nanofibers, which provides different release profiles
for model drugs separately loaded in either the sheath or the
core of the fiber. Homogenous, coaxial and triaxial fibers
containing a combination of materials (PCL, polycaprolactone;
PVP, polyvinylpyrrolidone) were fabricated. The drug
release profiles were simulated using two color dyes (KAB,
keyacid blue; KAU, keyacid uranine), whose release in
physiological solution was measured using optical absorption
as a function of time.....-
[center]ACS Appl. Mater. Interfaces 2013, 5, 8241−8245
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