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       #Post#: 42--------------------------------------------------
       polyurethane for cardiac tissue engineering application
       By: fmsbi Date: December 25, 2014, 6:24 pm
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       There has been a growing trend towards applying conducting
       polymers for electrically excitable cells to increase electrical
       signal propagation within the cell-loaded substrates. A novel
       biodegradable electroactive polyurethane containing aniline
       pentamer (AP-PU) was synthesized and fully characterized by
       spectroscopic methods. To tune the physico-chemical properties
       and biocompatibility, the AP-PU was blended with
       polycaprolactone (PCL). The presence of electroactive moieties
       and the electroactivity behavior of the prepared films were
       confirmed by UV-visible spectroscopy and cyclic voltammetry. A
       conventional four probe analysis demonstrated the electrical
       conductivity of the films in the semiconductor range
       (~10(-5)S/cm). MTT assays using L929 mouse fibroblast and human
       umbilical vein endothelial cells (HUVECs) showed that the
       prepared blend (PB) displayed more cytocompatibility compared
       with AP-PU due to the introduction of a biocompatible PCL
       moiety. The in vitro cell culture also confirmed that PB was as
       supportive as tissue culture plate. The antioxidant activity of
       the AP-PU was proved using 1,1-diphenyl-2-picrylhydrazyl (DPPH)
       scavenging assay by employing UV-vis spectroscopy. In vitro
       degradation tests conducted in phosphate-buffered saline, pH7.4
       and pH5.5, proved that the films were also biodegradable. The
       results of this study have highlighted the potential application
       of this bioelectroactive polyurethane as a platform substrate to
       study the effect of electrical signals on cell activities and to
       direct desirable cell function for tissue engineering
       applications.
       Copyright © 2014 Elsevier B.V. All rights reserved.
       Reference:
       Mater Sci Eng C Mater Biol Appl. 2014 Nov 1;44:24-37. doi:
       10.1016/j.msec.2014.07.061. Epub 2014 Aug 4.
       Synthesis, characterization and antioxidant activity of a novel
       electroactive and biodegradable polyurethane for cardiac tissue
       engineering application.
       Baheiraei N1, Yeganeh H2, Ai J3, Gharibi R4, Azami M1, Faghihi
       F1.
       Author information
       #Post#: 55--------------------------------------------------
       Re: polyurethane for cardiac tissue engineering application
       By: SSamani Date: December 26, 2014, 12:41 pm
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       Hi
       The article was shrunk to reduce size.
       Yours
       [center]Download link
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       #Post#: 56--------------------------------------------------
       Re: polyurethane for cardiac tissue engineering application
       By: nourani Date: December 26, 2014, 6:06 pm
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       [right]سلام و
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       دکتر
       سامانی
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       دارید.
       و پشتیبان
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       موفق باشید
       نورانی[/right]
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