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       #Post#: 68349--------------------------------------------------
       Labs with mild dwarfism (disproportionate.)
       By: guest114 Date: January 30, 2022, 2:31 am
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       Here's the paper. Just go to the cute floof photos (Figure 1)
       and enjoy.
       
  HTML https://pubmed.ncbi.nlm.nih.gov/23527306/
       
       Short background:  The gene involved is called COL11A2 (Type
       XI collagen, subunit 2 gene.)  It's one gene that helps make up
       a  fibril collagen (XI collagen) that helps regulate other
       collagens involved in forming the structure of cartilage and
       subsequent bone growth, and also a minor role in many other
       tissues, along with type V collagen (which is mutated in some
       cases of classical Ehler-Danlos syndrome.)
       In humans, this gene has been implicated in deafness, skeletal
       dysplasias.
       
       I admit the build reminds me of a Nova Scotia tolling duck
       retriever, and also maybe cocker spaniel crosses (that spaniel
       gene seems partly dominant, though, in crosses.)
       In this case, this gene is recessive and the pedigree
       analysis traces it back to a male lab born in 1966.
       What really struck me is that the male lab has splayed feet
       EXACTLY like my first service (a rottie-cocker) dog had. Same
       wide chest.  From the side, he didn't look like the top dog, he
       had a fused vertebra in his back near his hips and had a shorter
       body, more arched back (shorter front), and a curly tail (so
       more severe phenotype.)   But that nearly straight knee? Very
       similar!  The bigger looking head on the male lab, too.  That
       happy expression is great.
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