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       #Post#: 98--------------------------------------------------
       DRUGS including Tobacco and  Alcohol 
   DIR By: Blade of Grass
       Date: April 24, 2021, 8:31 am
       ---------------------------------------------------------
       I tried almost every street drug way back when. In order :
       Alcohol 15-17, Marijuana 17-19,
       LSD-Mescaline-Psilocybin-Opium-Meth-Barbiturates 18-19. Quit for
       14 years. Alchohol-Tabacoo-Marijuana 34-54. Then Pharmaceuticals
       after nervous breakdown...Celexa-Klonopin-Vaping-CBD-Medical
       Marijuana 56-present.
       
       Marijuana has changed in potency in the last 4 years to 4 times
       the strength it was before that, for 1000's of years. They
       produce hybrids that range from 97% Indica/
       3% Sativa  to 5% Indica/95% Sativa. 97% Indica will knock you
       out. 95% Sativa will get you totally WIRED. I have to micro dose
       it even with a 50/50 hybrid. (1/8th tsp)
       I find it absolutely amazing the varying effects the different
       strains make. There are so many Cannabinoid receptors in our
       bodies, and each strain affects different ones at different
       strengths. There are aprox 700 different strains. "Marijuana
       overdose" has jumped 100% in 2 years. (ER visits) It's legality
       is sweeping the world which is going to have all kinds of
       consequences. Issues of health, business/economy, world view,
       and crime to name a few. The potential of overdose is becoming a
       reality now and many remedies that Doctors use to help people
       quit an addition to it often include Benzodiazepines. These
       drugs are habit forming, and cause dependency and dangerous
       withdrawal symptoms.
       What a paradox.
       #Post#: 100--------------------------------------------------
       DRUGS including Tobacco and  Alcohol 
   DIR By: K-Dog
       Date: April 24, 2021, 11:17 am
       ---------------------------------------------------------
       [spoiler]
       --- Quote from: Blade of Grass link ---
       >
       > I tried almost every street drug way back when. In order :
       Alcohol 15-17, Marijuana 17-19,
       LSD-Mescaline-Psilocybin-Opium-Meth-Barbiturates 18-19. Quit for
       14 years. Alchohol-Tabacoo-Marijuana 34-54. Then Pharmaceuticals
       after nervous breakdown...Celexa-Klonopin-Vaping-CBD-Medical
       Marijuana 56-present.
       >
       > Marijuana has changed in potency in the last 4 years to 4
       times the strength it was before that, for 1000's of years. They
       produce hybrids that range from 97% Indica/
       > 3% Sativa  to 5% Indica/95% Sativa. 97% Indica will knock you
       out. 95% Sativa will get you totally WIRED. I have to micro dose
       it even with a 50/50 hybrid. (1/8th tsp)
       > I find it absolutely amazing the varying effects the different
       strains make. There are so many Cannabinoid receptors in our
       bodies, and each strain affects different ones at different
       strengths. There are aprox 700 different strains. "Marijuana
       overdose" has jumped 100% in 2 years. (ER visits) It's legality
       is sweeping the world which is going to have all kinds of
       consequences. Issues of health, business/economy, world view,
       and crime to name a few. The potential of overdose is becoming a
       reality now and many remedies that Doctors use to help people
       quit an addition to it often include Benzodiazepines. These
       drugs are habit forming, and cause dependency and dangerous
       withdrawal symptoms.
       > What a paradox.
       >
       --- End Quote ---
       [/spoiler]
       A friend and I made some Brownies a few years ago from a strain
       I developed named 'Stray Dog'.  We foolishly chomped down a
       couple of brownies each not thinking about the dosage.  Stray
       dog is very high in Sativa.  It makes your mind roam.
       We both fell asleep for 24 hours.  It was potent.  I don't mean
       23 hours.  It was a full day.
       Your pontification on overdose is amusing.
       --- Quote ---
       > “At present it is estimated that marijuana’s LD-50 is
       around1:20,000 or 1:40,000. In layman terms this means that in
       order to induce death a marijuana smoker would have to consume
       20,000 to 40,000 times as much marijuana as is contained in one
       marijuana cigarette. NIDA-supplied marijuana cigarettes weigh
       approximately .9 grams. A smoker would theoretically have to
       consume nearly 1,500 pounds of marijuana within about fifteen
       minutes to induce a lethal response.“At present it is estimated
       that marijuana’s LD-50 is around1:20,000 or 1:40,000. In layman
       terms this means that in order to induce death a marijuana
       smoker would have to consume 20,000 to 40,000 times as much
       marijuana as is contained in one marijuana cigarette.
       NIDA-supplied marijuana cigarettes weigh approximately .9 grams.
       A smoker would theoretically have to consume nearly 1,500 pounds
       of marijuana within about fifteen minutes to induce a lethal
       response.
       --- End Quote ---
       I don't microdose.
       #Post#: 103--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: Blade of Grass
       Date: April 24, 2021, 11:41 am
       ---------------------------------------------------------
       --- Quote from: K-Dog link ---
       >
       > [spoiler][quote author=Blade of Grass
       link=topic=13.msg98#msg98 date=1619271063]
       > I tried almost every street drug way back when. In order :
       Alcohol 15-17, Marijuana 17-19,
       LSD-Mescaline-Psilocybin-Opium-Meth-Barbiturates 18-19. Quit for
       14 years. Alchohol-Tabacoo-Marijuana 34-54. Then Pharmaceuticals
       after nervous breakdown...Celexa-Klonopin-Vaping-CBD-Medical
       Marijuana 56-present.
       >
       > Marijuana has changed in potency in the last 4 years to 4
       times the strength it was before that, for 1000's of years. They
       produce hybrids that range from 97% Indica/
       > 3% Sativa  to 5% Indica/95% Sativa. 97% Indica will knock you
       out. 95% Sativa will get you totally WIRED. I have to micro dose
       it even with a 50/50 hybrid. (1/8th tsp)
       > I find it absolutely amazing the varying effects the different
       strains make. There are so many Cannabinoid receptors in our
       bodies, and each strain affects different ones at different
       strengths. There are aprox 700 different strains. "Marijuana
       overdose" has jumped 100% in 2 years. (ER visits) It's legality
       is sweeping the world which is going to have all kinds of
       consequences. Issues of health, business/economy, world view,
       and crime to name a few. The potential of overdose is becoming a
       reality now and many remedies that Doctors use to help people
       quit an addition to it often include Benzodiazepines. These
       drugs are habit forming, and cause dependency and dangerous
       withdrawal symptoms.
       > What a paradox.
       >
       --- End Quote ---
       [/spoiler]
       A friend and I made some Brownies a few years ago from a strain
       I developed named 'Stray Dog'.  We foolishly chomped down a
       couple of brownies each not thinking about the dosage.  Stray
       dog is very high in Sativa.  It makes your mind roam.
       We both fell asleep for 24 hours.  It was potent.  I don't mean
       23 hours.  It was a full day.
       Your pontification on overdose is amusing.
       --- Quote ---
       > “At present it is estimated that marijuana’s LD-50 is
       around1:20,000 or 1:40,000. In layman terms this means that in
       order to induce death a marijuana smoker would have to consume
       20,000 to 40,000 times as much marijuana as is contained in one
       marijuana cigarette. NIDA-supplied marijuana cigarettes weigh
       approximately .9 grams. A smoker would theoretically have to
       consume nearly 1,500 pounds of marijuana within about fifteen
       minutes to induce a lethal response.“At present it is estimated
       that marijuana’s LD-50 is around1:20,000 or 1:40,000. In layman
       terms this means that in order to induce death a marijuana
       smoker would have to consume 20,000 to 40,000 times as much
       marijuana as is contained in one marijuana cigarette.
       NIDA-supplied marijuana cigarettes weigh approximately .9 grams.
       A smoker would theoretically have to consume nearly 1,500 pounds
       of marijuana within about fifteen minutes to induce a lethal
       response.
       --- End Quote ---
       I don't microdose.
       [/quote]
       Your right about my "pontification" misinformation. I heard it
       from a friend, and just found out what I got wrong. Here is the
       abstract with the stats.
       Abstract
       Background: On October 17, 2018, the Cannabis Act decriminalized
       the recreational use of cannabis in Canada. This study seeks to
       determine how legalization of cannabis has impacted emergency
       department (ED) visits for acute cannabis intoxication.
       Methods: We conducted a retrospective chart review at an
       academic ED in Hamilton, Ontario. We assessed all visits with a
       cannabis-related ICD-10 discharge code 6 months before and after
       legalization (October 17, 2018) to determine cases of acute
       cannabis intoxication. The primary outcome was the rate of ED
       visits. Secondary outcomes included number of visits distributed
       by age, length of stay, co-ingestions, and clinical course in
       the emergency department (investigations and treatment).
       Results: There was no difference in the overall rate of ED
       visits following legalization (2.44 vs. 2.94 visits/1000, p =
       0.27). However, we noted a 56% increase in visits among adults
       aged 18-29 (p = 0.03). Following legalization, a larger portion
       of patients required observation without interventions (25% vs
       48%, p < 0.05). Bloodwork and imaging studies decreased (53% vs.
       12%, p < 0.05; 29% vs. 2%, p < 0.05); however, treatment with
       benzodiazepines increased (24% vs. 51%, p < 0.05).
       Conclusions: Legalization was not associated with a change in
       the rate of cannabis-related ED visits in our study. More
       research is needed regarding changing methods of cannabis
       ingestion and trends among specific age groups.
       
  HTML https://pubmed.ncbi.nlm.nih.gov/33731003/
       #Post#: 119--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: Phil Potts
       Date: April 24, 2021, 5:01 pm
       ---------------------------------------------------------
       Certainly there was a massive jump in the strength of hooch in
       the 90s with the intro of hydroponic growing here, virtually all
       of it done in the state with the lax laws. I'm guessing if there
       was a big jump in your local strength 4 yrs ago, that's when
       decriminalisation and hydroponic growing started.
       #Post#: 120--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: K-Dog
       Date: April 24, 2021, 7:19 pm
       ---------------------------------------------------------
       [spoiler]
       --- Quote from: Blade of Grass link ---
       >
       > [quote author=K-Dog link=topic=13.msg100#msg100
       date=1619281076]
       > [quote author=Blade of Grass link=topic=13.msg98#msg98
       date=1619271063]
       > I tried almost every street drug way back when. In order :
       Alcohol 15-17, Marijuana 17-19,
       LSD-Mescaline-Psilocybin-Opium-Meth-Barbiturates 18-19. Quit for
       14 years. Alchohol-Tabacoo-Marijuana 34-54. Then Pharmaceuticals
       after nervous breakdown...Celexa-Klonopin-Vaping-CBD-Medical
       Marijuana 56-present.
       >
       > Marijuana has changed in potency in the last 4 years to 4
       times the strength it was before that, for 1000's of years. They
       produce hybrids that range from 97% Indica/
       > 3% Sativa  to 5% Indica/95% Sativa. 97% Indica will knock you
       out. 95% Sativa will get you totally WIRED. I have to micro dose
       it even with a 50/50 hybrid. (1/8th tsp)
       > I find it absolutely amazing the varying effects the different
       strains make. There are so many Cannabinoid receptors in our
       bodies, and each strain affects different ones at different
       strengths. There are aprox 700 different strains. "Marijuana
       overdose" has jumped 100% in 2 years. (ER visits) It's legality
       is sweeping the world which is going to have all kinds of
       consequences. Issues of health, business/economy, world view,
       and crime to name a few. The potential of overdose is becoming a
       reality now and many remedies that Doctors use to help people
       quit an addition to it often include Benzodiazepines. These
       drugs are habit forming, and cause dependency and dangerous
       withdrawal symptoms.
       > What a paradox.
       >
       --- End Quote ---
       A friend and I made some Brownies a few years ago from a strain
       I developed named 'Stray Dog'.  We foolishly chomped down a
       couple of brownies each not thinking about the dosage.  Stray
       dog is very high in Sativa.  It makes your mind roam.
       We both fell asleep for 24 hours.  It was potent.  I don't mean
       23 hours.  It was a full day.
       Your pontification on overdose is amusing.
       --- Quote ---
       > “At present it is estimated that marijuana’s LD-50 is
       around1:20,000 or 1:40,000. In layman terms this means that in
       order to induce death a marijuana smoker would have to consume
       20,000 to 40,000 times as much marijuana as is contained in one
       marijuana cigarette. NIDA-supplied marijuana cigarettes weigh
       approximately .9 grams. A smoker would theoretically have to
       consume nearly 1,500 pounds of marijuana within about fifteen
       minutes to induce a lethal response.“At present it is estimated
       that marijuana’s LD-50 is around1:20,000 or 1:40,000. In layman
       terms this means that in order to induce death a marijuana
       smoker would have to consume 20,000 to 40,000 times as much
       marijuana as is contained in one marijuana cigarette.
       NIDA-supplied marijuana cigarettes weigh approximately .9 grams.
       A smoker would theoretically have to consume nearly 1,500 pounds
       of marijuana within about fifteen minutes to induce a lethal
       response.
       --- End Quote ---
       I don't microdose.
       [/quote]
       Your right about my "pontification" misinformation. I heard it
       from a friend, and just found out what I got wrong. Here is the
       abstract with the stats.
       Abstract
       Background: On October 17, 2018, the Cannabis Act decriminalized
       the recreational use of cannabis in Canada. This study seeks to
       determine how legalization of cannabis has impacted emergency
       department (ED) visits for acute cannabis intoxication.
       Methods: We conducted a retrospective chart review at an
       academic ED in Hamilton, Ontario. We assessed all visits with a
       cannabis-related ICD-10 discharge code 6 months before and after
       legalization (October 17, 2018) to determine cases of acute
       cannabis intoxication. The primary outcome was the rate of ED
       visits. Secondary outcomes included number of visits distributed
       by age, length of stay, co-ingestions, and clinical course in
       the emergency department (investigations and treatment).
       Results: There was no difference in the overall rate of ED
       visits following legalization (2.44 vs. 2.94 visits/1000, p =
       0.27). However, we noted a 56% increase in visits among adults
       aged 18-29 (p = 0.03). Following legalization, a larger portion
       of patients required observation without interventions (25% vs
       48%, p < 0.05). Bloodwork and imaging studies decreased (53% vs.
       12%, p < 0.05; 29% vs. 2%, p < 0.05); however, treatment with
       benzodiazepines increased (24% vs. 51%, p < 0.05).
       Conclusions: Legalization was not associated with a change in
       the rate of cannabis-related ED visits in our study. More
       research is needed regarding changing methods of cannabis
       ingestion and trends among specific age groups.
       
  HTML https://pubmed.ncbi.nlm.nih.gov/33731003/
       [/quote][/spoiler]
       As a dedicated stoner I find the whole thing bizarre.  I found
       out from my first exposure at 16 that the 'devil weed' was
       nothing of the kind.  It was years before I became a regular
       user yet I had already learned early that there were no such
       thing as hospital visits from weed.  And one hell of a lot of
       negative propaganda about it.
       Some newbies can get too high but experienced users don't get to
       a point of intoxication beyond that which would interfere with
       normal functioning without getting a splitting, I want to die,
       headache first.  Aspirin does wonders in that situation
       especially if you avoid aspirin in general as I do.  Cannabis
       turns out to be a stimulant much like coffee and is perhaps only
       twice as strong after your tolerance reaches show dog levels.
       But it does take many years of serious dedication before your
       tolerance builds up a prizewinning grade.  Then your brain is
       rewired around any generated mental confusions.
       And the good **** has been around for a long time now.  Good
       seeds came around about twenty years ago.  Mail order from
       Canada was the way to get them then.  About the only good thing
       legalization has done is allow for more variety of strain
       choices.  When it was illegal people only wanted to grow skunk.
       I think skunk sucks.
       #Post#: 121--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: Phil Potts
       Date: April 24, 2021, 8:05 pm
       ---------------------------------------------------------
       --- Quote from: K-Dog link ---
       >
       > [spoiler][quote author=Blade of Grass
       link=topic=13.msg103#msg103 date=1619282467]
       > [quote author=K-Dog link=topic=13.msg100#msg100
       date=1619281076]
       > [quote author=Blade of Grass link=topic=13.msg98#msg98
       date=1619271063]
       > I tried almost every street drug way back when. In order :
       Alcohol 15-17, Marijuana 17-19,
       LSD-Mescaline-Psilocybin-Opium-Meth-Barbiturates 18-19. Quit for
       14 years. Alchohol-Tabacoo-Marijuana 34-54. Then Pharmaceuticals
       after nervous breakdown...Celexa-Klonopin-Vaping-CBD-Medical
       Marijuana 56-present.
       >
       > Marijuana has changed in potency in the last 4 years to 4
       times the strength it was before that, for 1000's of years. They
       produce hybrids that range from 97% Indica/
       > 3% Sativa  to 5% Indica/95% Sativa. 97% Indica will knock you
       out. 95% Sativa will get you totally WIRED. I have to micro dose
       it even with a 50/50 hybrid. (1/8th tsp)
       > I find it absolutely amazing the varying effects the different
       strains make. There are so many Cannabinoid receptors in our
       bodies, and each strain affects different ones at different
       strengths. There are aprox 700 different strains. "Marijuana
       overdose" has jumped 100% in 2 years. (ER visits) It's legality
       is sweeping the world which is going to have all kinds of
       consequences. Issues of health, business/economy, world view,
       and crime to name a few. The potential of overdose is becoming a
       reality now and many remedies that Doctors use to help people
       quit an addition to it often include Benzodiazepines. These
       drugs are habit forming, and cause dependency and dangerous
       withdrawal symptoms.
       > What a paradox.
       >
       --- End Quote ---
       A friend and I made some Brownies a few years ago from a strain
       I developed named 'Stray Dog'.  We foolishly chomped down a
       couple of brownies each not thinking about the dosage.  Stray
       dog is very high in Sativa.  It makes your mind roam.
       We both fell asleep for 24 hours.  It was potent.  I don't mean
       23 hours.  It was a full day.
       Your pontification on overdose is amusing.
       --- Quote ---
       > “At present it is estimated that marijuana’s LD-50 is
       around1:20,000 or 1:40,000. In layman terms this means that in
       order to induce death a marijuana smoker would have to consume
       20,000 to 40,000 times as much marijuana as is contained in one
       marijuana cigarette. NIDA-supplied marijuana cigarettes weigh
       approximately .9 grams. A smoker would theoretically have to
       consume nearly 1,500 pounds of marijuana within about fifteen
       minutes to induce a lethal response.“At present it is estimated
       that marijuana’s LD-50 is around1:20,000 or 1:40,000. In layman
       terms this means that in order to induce death a marijuana
       smoker would have to consume 20,000 to 40,000 times as much
       marijuana as is contained in one marijuana cigarette.
       NIDA-supplied marijuana cigarettes weigh approximately .9 grams.
       A smoker would theoretically have to consume nearly 1,500 pounds
       of marijuana within about fifteen minutes to induce a lethal
       response.
       --- End Quote ---
       I don't microdose.
       [/quote]
       Your right about my "pontification" misinformation. I heard it
       from a friend, and just found out what I got wrong. Here is the
       abstract with the stats.
       Abstract
       Background: On October 17, 2018, the Cannabis Act decriminalized
       the recreational use of cannabis in Canada. This study seeks to
       determine how legalization of cannabis has impacted emergency
       department (ED) visits for acute cannabis intoxication.
       Methods: We conducted a retrospective chart review at an
       academic ED in Hamilton, Ontario. We assessed all visits with a
       cannabis-related ICD-10 discharge code 6 months before and after
       legalization (October 17, 2018) to determine cases of acute
       cannabis intoxication. The primary outcome was the rate of ED
       visits. Secondary outcomes included number of visits distributed
       by age, length of stay, co-ingestions, and clinical course in
       the emergency department (investigations and treatment).
       Results: There was no difference in the overall rate of ED
       visits following legalization (2.44 vs. 2.94 visits/1000, p =
       0.27). However, we noted a 56% increase in visits among adults
       aged 18-29 (p = 0.03). Following legalization, a larger portion
       of patients required observation without interventions (25% vs
       48%, p < 0.05). Bloodwork and imaging studies decreased (53% vs.
       12%, p < 0.05; 29% vs. 2%, p < 0.05); however, treatment with
       benzodiazepines increased (24% vs. 51%, p < 0.05).
       Conclusions: Legalization was not associated with a change in
       the rate of cannabis-related ED visits in our study. More
       research is needed regarding changing methods of cannabis
       ingestion and trends among specific age groups.
       
  HTML https://pubmed.ncbi.nlm.nih.gov/33731003/
       [/quote][/spoiler]
       As a dedicated stoner I find the whole thing bizarre.  I found
       out from my first exposure at 16 that the 'devil weed' was
       nothing of the kind.  It was years before I became a regular
       user yet I had already learned early that there were no such
       thing as hospital visits from weed.  And one hell of a lot of
       negative propaganda about it.
       Some newbies can get too high but experienced users don't get to
       a point of intoxication beyond that which would interfere with
       normal functioning without getting a splitting, I want to die,
       headache first.  Aspirin does wonders in that situation
       especially if you avoid aspirin in general as I do.  Cannabis
       turns out to be a stimulant much like coffee is and perhaps only
       twice as strong after your tolerance reaches show dog levels.
       But it does take many years of serious dedication before your
       tolerance builds up a prizewinning level.  Then your brain is
       rewired around any generated mental confusions.
       And the good **** has been around for a long time now.  Good
       seeds came around about twenty years ago.  Mail order from
       Canada was the way to get them then.  About the only good thing
       legalization has done is allow for more variety of strains.
       When it was illegal people only wanted to grow skunk.  I think
       skunk sucks.
       [/quote]
       I beg to differ on the stimulant 'much like coffee'. You
       increase HR and strong diuretic like coffee, but synaptic firing
       is slowed, that's the high you either enjoy or don't enjoy. As
       you said, people who smoke every day for years habituate and
       build tolerance so the effect is not noticeable, but they can
       still have elevated paranoia. Mike Tyson said to reporters after
       his recent comeback exhibition match, that he had been smoking
       before the fight. No casual user could have done that as their
       reflexes and coordination are slowed.
       There are certainly more damaging drugs out there in terms of
       impact to health, aggression, hallucination and disinhibition
       which can lead to regrettable impulses. James Garner was open
       about his use for pain relief from arthritis, others re back
       pain long before it was legal anywhere in the west other than
       Amsterdam. Now even symptoms of autism are shown to be reduced
       by scientific research. Of course it depends on what state you
       live in for whether it is legal to grow, buy, or have
       prescribed.
       #Post#: 122--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: K-Dog
       Date: April 24, 2021, 8:13 pm
       ---------------------------------------------------------
       --- Quote ---
       > but they can still have elevated paranoia.
       --- End Quote ---
       It is not paranoia when people really do follow you.
       #Post#: 124--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: K-Dog
       Date: April 24, 2021, 11:17 pm
       ---------------------------------------------------------
       [spoiler]
       --- Quote from: BuddyJ link ---
       >
       > Don't have any personal knowledge of drugs, tobacco, alcohol,
       whatever. My experience with the aftermath of family and
       friend's enthusiastic use of these substances was a bit off
       putting though. Having a somewhat obsessive/compulsive
       personality in the first place, it never seemed like a good idea
       to get involved in any of it.
       >
       --- End Quote ---
       [/spoiler]
       --- Quote ---
       > Raoul Duke: We were somewhere around Barstow, on the edge of
       the desert, when the drugs began to take hold. I remember saying
       something like: I feel a bit lightheaded. Maybe you should
       drive. Suddenly, there was a terrible roar all around us, and
       the sky was full with what looked like huge bats, all swooping
       and screeching and diving around the car, and a voice was
       screaming: Holy Jesus. What are these goddamn animals?
       > Dr. Gonzo: Did you say something?
       > Raoul Duke: Hm? Never mind. It’s your turn to drive.
       > Raoul Duke: No point in mentioning these bats, I thought. Poor
       bastard will see them soon enough.
       --- End Quote ---
       #Post#: 129--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: Blade of Grass
       Date: April 25, 2021, 4:10 am
       ---------------------------------------------------------
       --- Quote from: K-Dog link ---
       >
       > [spoiler][quote author=Blade of Grass
       link=topic=13.msg103#msg103 date=1619282467]
       > [quote author=K-Dog link=topic=13.msg100#msg100
       date=1619281076]
       > [quote author=Blade of Grass link=topic=13.msg98#msg98
       date=1619271063]
       > I tried almost every street drug way back when. In order :
       Alcohol 15-17, Marijuana 17-19,
       LSD-Mescaline-Psilocybin-Opium-Meth-Barbiturates 18-19. Quit for
       14 years. Alchohol-Tabacoo-Marijuana 34-54. Then Pharmaceuticals
       after nervous breakdown...Celexa-Klonopin-Vaping-CBD-Medical
       Marijuana 56-present.
       >
       > Marijuana has changed in potency in the last 4 years to 4
       times the strength it was before that, for 1000's of years. They
       produce hybrids that range from 97% Indica/
       > 3% Sativa  to 5% Indica/95% Sativa. 97% Indica will knock you
       out. 95% Sativa will get you totally WIRED. I have to micro dose
       it even with a 50/50 hybrid. (1/8th tsp)
       > I find it absolutely amazing the varying effects the different
       strains make. There are so many Cannabinoid receptors in our
       bodies, and each strain affects different ones at different
       strengths. There are aprox 700 different strains. "Marijuana
       overdose" has jumped 100% in 2 years. (ER visits) It's legality
       is sweeping the world which is going to have all kinds of
       consequences. Issues of health, business/economy, world view,
       and crime to name a few. The potential of overdose is becoming a
       reality now and many remedies that Doctors use to help people
       quit an addition to it often include Benzodiazepines. These
       drugs are habit forming, and cause dependency and dangerous
       withdrawal symptoms.
       > What a paradox.
       >
       --- End Quote ---
       A friend and I made some Brownies a few years ago from a strain
       I developed named 'Stray Dog'.  We foolishly chomped down a
       couple of brownies each not thinking about the dosage.  Stray
       dog is very high in Sativa.  It makes your mind roam.
       We both fell asleep for 24 hours.  It was potent.  I don't mean
       23 hours.  It was a full day.
       Your pontification on overdose is amusing.
       --- Quote ---
       > “At present it is estimated that marijuana’s LD-50 is
       around1:20,000 or 1:40,000. In layman terms this means that in
       order to induce death a marijuana smoker would have to consume
       20,000 to 40,000 times as much marijuana as is contained in one
       marijuana cigarette. NIDA-supplied marijuana cigarettes weigh
       approximately .9 grams. A smoker would theoretically have to
       consume nearly 1,500 pounds of marijuana within about fifteen
       minutes to induce a lethal response.“At present it is estimated
       that marijuana’s LD-50 is around1:20,000 or 1:40,000. In layman
       terms this means that in order to induce death a marijuana
       smoker would have to consume 20,000 to 40,000 times as much
       marijuana as is contained in one marijuana cigarette.
       NIDA-supplied marijuana cigarettes weigh approximately .9 grams.
       A smoker would theoretically have to consume nearly 1,500 pounds
       of marijuana within about fifteen minutes to induce a lethal
       response.
       --- End Quote ---
       I don't microdose.
       [/quote]
       Your right about my "pontification" misinformation. I heard it
       from a friend, and just found out what I got wrong. Here is the
       abstract with the stats.
       Abstract
       Background: On October 17, 2018, the Cannabis Act decriminalized
       the recreational use of cannabis in Canada. This study seeks to
       determine how legalization of cannabis has impacted emergency
       department (ED) visits for acute cannabis intoxication.
       Methods: We conducted a retrospective chart review at an
       academic ED in Hamilton, Ontario. We assessed all visits with a
       cannabis-related ICD-10 discharge code 6 months before and after
       legalization (October 17, 2018) to determine cases of acute
       cannabis intoxication. The primary outcome was the rate of ED
       visits. Secondary outcomes included number of visits distributed
       by age, length of stay, co-ingestions, and clinical course in
       the emergency department (investigations and treatment).
       Results: There was no difference in the overall rate of ED
       visits following legalization (2.44 vs. 2.94 visits/1000, p =
       0.27). However, we noted a 56% increase in visits among adults
       aged 18-29 (p = 0.03). Following legalization, a larger portion
       of patients required observation without interventions (25% vs
       48%, p < 0.05). Bloodwork and imaging studies decreased (53% vs.
       12%, p < 0.05; 29% vs. 2%, p < 0.05); however, treatment with
       benzodiazepines increased (24% vs. 51%, p < 0.05).
       Conclusions: Legalization was not associated with a change in
       the rate of cannabis-related ED visits in our study. More
       research is needed regarding changing methods of cannabis
       ingestion and trends among specific age groups.
       
  HTML https://pubmed.ncbi.nlm.nih.gov/33731003/
       [/quote][/spoiler]
       As a dedicated stoner I find the whole thing bizarre.  I found
       out from my first exposure at 16 that the 'devil weed' was
       nothing of the kind.  It was years before I became a regular
       user yet I had already learned early that there were no such
       thing as hospital visits from weed.  And one hell of a lot of
       negative propaganda about it.
       Some newbies can get too high but experienced users don't get to
       a point of intoxication beyond that which would interfere with
       normal functioning without getting a splitting, I want to die,
       headache first.  Aspirin does wonders in that situation
       especially if you avoid aspirin in general as I do.  Cannabis
       turns out to be a stimulant much like coffee and is perhaps only
       twice as strong after your tolerance reaches show dog levels.
       But it does take many years of serious dedication before your
       tolerance builds up a prizewinning grade.  Then your brain is
       rewired around any generated mental confusions.
       And the good **** has been around for a long time now.  Good
       seeds came around about twenty years ago.  Mail order from
       Canada was the way to get them then.  About the only good thing
       legalization has done is allow for more variety of strain
       choices.  When it was illegal people only wanted to grow skunk.
       I think skunk sucks.
       [/quote]
       What strains do you like?  I am using Galeto, Lemon Haze, and
       Sudae Driver. The choices here are slim compared to like where
       you are or Colorado
       The ER visit misunderstanding was bewildering to me also. I have
       never "flipped out" with weed. Had some trouble with LSD once
       though...took too much, put me right up there in the "music of
       the spheres". :)
       #Post#: 130--------------------------------------------------
       Re: DRUGS including Tobacco and  Alcohol 
   DIR By: Blade of Grass
       Date: April 25, 2021, 4:26 am
       ---------------------------------------------------------
       --- Quote from: K-Dog link ---
       >
       > [spoiler][quote author=BuddyJ link=topic=13.msg123#msg123
       date=1619323413]
       > Don't have any personal knowledge of drugs, tobacco, alcohol,
       whatever. My experience with the aftermath of family and
       friend's enthusiastic use of these substances was a bit off
       putting though. Having a somewhat obsessive/compulsive
       personality in the first place, it never seemed like a good idea
       to get involved in any of it.
       >
       --- End Quote ---
       [/spoiler]
       --- Quote ---
       > Raoul Duke: We were somewhere around Barstow, on the edge of
       the desert, when the drugs began to take hold. I remember saying
       something like: I feel a bit lightheaded. Maybe you should
       drive. Suddenly, there was a terrible roar all around us, and
       the sky was full with what looked like huge bats, all swooping
       and screeching and diving around the car, and a voice was
       screaming: Holy Jesus. What are these goddamn animals?
       > Dr. Gonzo: Did you say something?
       > Raoul Duke: Hm? Never mind. It’s your turn to drive.
       > Raoul Duke: No point in mentioning these bats, I thought. Poor
       bastard will see them soon enough.
       --- End Quote ---
       [/quote]
       LOL...I remember the first time I took LSD. 18 years old,
       walking on the sidewalk and thinking I was feeling it...but 30
       minutes later everything started getting odd. Everything lit up
       like an animated Pixel movie. I was so naive I wondered into
       someones yard and picked some flowers and gazed at them and went
       into bliss and started crying. I felt at ONE with the whole
       universe. Ha! Then I walked right through a red light holding
       the flowers and crying, a driver honked at me and gave me the
       thumbs up. :)
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