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#Post#: 2466--------------------------------------------------
Coming soon: Female viagr.a
DIR By: lubhan
Date: December 16, 2016, 4:50 am
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A female equivalent of **** could soon be available to help
women achieve the Big O, claim scientists.
A team working for Pfizer, the pharmaceutical firm behind ****,
in Sandwich, Kent, has uncovered a substance that boosts female
sexual arousal, increasing her chance of orgasm.
The findings could pave the way for a drug similar in effect to
****, which has helped countless men.
In the study, using a novel prototype drug, researchers
discovered more about the mechanisms underlying female sexual
arousal.
The boffins found that electrically stimulating the pelvic nerve
increases blood flow to the genitalia, and that this effect was
enhanced if they also gave a prototype drug (UK-414,495).
They believe that the drug acts by blocking the breakdown of an
internal chemical messenger that plays a key role in increasing
blood flow during sexual arousal.
When women become aroused, blood flow increases to the ****,
labia and clitoris. This causes the organs to swell, and the
**** to relax, as well as increasing vaginal lubrication and the
sensitivity of the genitalia.
Female sexual arousal disorder (FSAD) affects up to 40percent of
women irrespective of age. These women find that their genital
organs do not respond to sexual stimulation, they find arousal
difficult and this causes them to become distressed.
"Before this work, we knew surprisingly little about the
processes that control all of these changes," says the lead
researcher in the project Chris Wayman. "Now we are beginning to
establish the pathways involved in sexual arousal scientists may
be able to find ways of helping women who would like to overcome
FSAD."
In the study, researchers stimulated the pelvic nerve and
measured changes in genital organs. They believed the genital
arousal occurred because stimulation of the nerve triggered the
release of vasoactive intestinal peptide (VIP), a well-known
neurotransmitter. VIP has only a short-lived effect, because it
is soon broken down by an enzyme called Neutral Endopeptidase
(NEP). The researchers believe that their prototype drug
increased the arousal because it blocked NEP's ability to break
down VIP, therefore letting the VIP have a more powerful and
prolonged effect increasing arousal.
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