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SUB
DIR By: Admin
Date: March 31, 2023, 10:51 pm
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#Post#: 678--------------------------------------------------
Re: SUB
DIR By: Admin
Date: March 26, 2024, 3:31 pm
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AI ON DMSO/MSM SCIENCE
_A study on monkeys of 2-week, high-dose, oral DMSO found that
76% was excreted (60% as DMSO, 16% as MSM). That leaves 24% that
was not excreted, but some of that was likely exhaled. The rest
would apparently perhaps have converted mostly to MSM, which is
2 methyl groups and one sulfur dioxide and there is evidence
that both are used nutritionally.
_Methylation is when the body adds a methyl group, CH3, to
another molecule. It helps control which genes are active, make
and process brain chemicals, build cell membranes, make DNA
components, and process certain hormones and chemicals.
_The strongest hint that MSM helps methylation is a human
liver-cell study using deuterium-labeled MSM. Researchers found
that labeled methyl groups from MSM appeared in newly methylated
DNA products, showing that MSM’s methyl groups can enter
cellular methylation chemistry under laboratory conditions.1,2
HTML https://pubmed.ncbi.nlm.nih.gov/36469606/
HTML https://pmc.ncbi.nlm.nih.gov/articles/PMC10239780/
That is meaningful biochemical evidence, but it is not yet proof
in people taking MSM supplements. The next evidence needed would
be a human trial showing that oral MSM changes SAMe-related
methylation activity or specific methylation outcomes in blood
or tissues.
_The best-supported specific use of sulfur from MSM is that it
can enter the body’s inorganic sulfate pool. From there, the
body activates sulfate into PAPS and uses it to attach sulfate
groups to important molecules. Animal radiolabel studies also
show that some MSM-derived sulfur can be incorporated into body
proteins, but exactly how much reaches each pathway in humans is
not well measured.3,4
HTML https://pmc.ncbi.nlm.nih.gov/articles/PMC5793247/
HTML https://pmc.ncbi.nlm.nih.gov/articles/PMC9385285/
_The study found only about 1% of the labeled MSM sulfur in
protein methionine/cysteine, so it showed that this happened a
little.5,6
HTML https://pubmed.ncbi.nlm.nih.gov/3736326/
HTML https://pubs.acs.org/doi/abs/10.1021/pr500629t
SLOANE ON DMSO & MSM
HTML https://www.curezone.org/forums/fm.asp?i=1442125
_DMSO can be a good thing if used carefully and properly. Though
I generally do not recommend it due to the hassles and safety
issues. My biggest concern is people not cleaning the
application site properly. Because DMSO crosses the skin so
rapidly it will also take pretty much anything it contacts
through the skin with it in to the bloodstream. This includes
soap scum. So the area needs to be cleaned really well with soap
and water, then again with rubbing alcohol to remove the soap
scum before applying the DMSO.
_My other big concern is the possible reaction of the
hypochlorite, improperly being referred to as chlorine dioxide
(a very toxic gas), with the DMSO. This is based on the Ramirez
case a while back in which there was a conversion of the DMSO a
cancer patient was using in to toxic DMSO4.
_Anyway, hypochlorites are oxidizers, and there is not enough
known about interactions between DMSO and oxidizers. We do know
that we can oxidize DMSO with heat in to DMSO2, also known as
methylsulfonylmethane (MSM), but not with stronger oxidizers.
_Hypochlorites make me nervous anyway. Again very little is
known about their action in the body or interactions with other
compounds. Chlorine is needed by the body, but it also forms
some of the most toxic compounds known to man such as nerve
agents.
_MSM is good, but I still prefer to get my sulfur from natural
sources as much as possible. Commercial MSM is not natural.
Again it is synthesized from the industrial solvent DMSO.
DMSO DANGER
HTML https://www.curezone.org/forums/fm.asp?i=1448951
_You need to be careful with mixing chemicals. Remember the
Ramirez case? The lady was using DMSO, which researchers believe
was oxidized in the powerful toxin DMSO4 (dimethylsulfate),
which ended up hospitalizing a lot of people. Point is that the
chemical reaction between DMSO and MMS, an oxidizer, is unknown.
And there is at least one case where it looks like the oxidation
of DMSO has lead to the formation of a poison in a human. Here
is a link to the story:
HTML https://www.discovermagazine.com/analysis-of-a-toxic-death-14125
_Commercial MSM is produced by the heating of DMSO, which adds
an oxygen atom creating DMSO2, otherwise known as MSM. Over all
DMSO is great for pain and swelling, but due to the instant
garlicky smell and the hassles of trying to use it safely I will
pass myself.
HTML https://www.curezone.org/forums/fm.asp?i=1836747#i
_As far as DMSO goes I really DO NOT recommend people playing
with it due to safety reasons. The biggest problem with DMSO is
that it travels through the skin at such a fast rate that it
actually carries other compounds on the skin with it in to the
bloodstream. This includes things such as dirt, bacteria, soap
scum, etc.
_If someone does decide to still use it they should NEVER use it
in combination with ozone. I posted about the Ramirez case a few
times that explains why:
HTML http://curezone.org/forums/fm.asp?i=1448951
HTML http://curezone.org/forums/fm.asp?i=1457000
READER USED DMSO ON A BAD BURN
_A reader said she accidentally poured boiling water over the
back of her hand. The pain from the burn masked the sting of the
DMSO that she literally poured straight over her hand. {I guess
some people are more sensitive. I don't notice any sting myself
when I apply DMSO to my skin. The most I sense is a small
tickle.} She used DMSO twice that day and there was no more pain
or redness. In the morning she used it once more just to be
sure. No redness, no pain, no blisters. About a week later,
small amounts of skin on the hand peeled away. It was gentle and
hardly noticed. Skin was replaced. That was it. The hand healed
completely with no noticeable anything wrong. The skin on the
back of the burnt hand was then smoother than that on the
unburnt hand. Her son took DMSO and his kidney issues healed
quickly.
READER USED DMSO ON TWITCHING
_A reader was diagnosed with cervical spinal stenosis (narrowing
of the spinal canal in the neck vertebrae) and was scheduled for
surgery, but after having misgivings, canceled the operation two
days before it was scheduled. For a decade afterward, the reader
remained surgery-free and felt confident in the decision. Ten
years later, while reading in bed, the reader developed
persistent twitching in the left arm that worsened over two
days. Remembering prior personal success using DMSO for joint
and tendon issues, the reader mixed DMSO with aloe vera and
applied it to the back of the neck about three times daily. By
the following day, the twitching was much less noticeable, and
after roughly three days it stopped. The reader sees this as a
strong personal endorsement of DMSO. {For twitches I generally
suspect need for more magnesium.}
SLOANE ON TWITCHING
HTML https://www.curezone.org/forums/fm.asp?i=1614290
_Muscle twitching (tics) can usually be halted with magnesium
supplementation. Look for magnesium malate or citrate and avoid
magnesium oxide altogether.
SLOANE ON QUITTING INHALERS
HTML https://www.curezone.org/forums/fm.asp?i=1713887#i
youtube.com/watch?v=v5LnaOwvJIk
SLOANE ON MSM FOR SULFUR
HTML https://www.curezone.org/forums/fm.asp?i=1819974
I rarely recommend MSM because sulfur is so abundant in the diet
that deficiencies are extremely rare.
MSM FOR KNEE PAIN
HTML https://www.curezone.org/forums/fm.asp?i=1473585
(Re
HTML https://www.curezone.org/forums/fm.asp?i=1473556#i)
_There are quite a few supplements that can help, but the main
ones I would focus on would be gelatin, MSM (methylsulfonyl
methane), and seaweeds. Nettle leaf, alfalfa and gotu kola are
also good choices. These will supply the nutrition to rebuild
the cartilage, and the gotu kola will help speed the
regeneration.
I would skip the DMSO unless you really know what you are doing.
Anything on the skin when you apply it, including soap residue,
will be carried right in to the bloodstream. I would stick to
the MSM, which is actually DMSO2.
MSM PAIN KILLER
HTML https://www.curezone.org/forums/fm.asp?i=1528442
_(Quoting a defunct website:) MSM ... is a powerful painkiller
with anti-inflammatory, anti-spasmodic and analgesic properties,
and it inhibits the transmission of pain impulses. In a
double-blind study conducted at the UCLA School of Medicine in
America, researchers showed that 80 per cent pain control was
achieved within six weeks in degenerative arthritis patients
receiving MSM, but only a negligible improvement was observed in
the control group. It is available both as a dietary supplement
and as a cream for topical application.
MSM & HERBS FOR ARTHRITIS
_"I have been given some msm powder, glutamine powder (mixed
with soluble fibre) and lots of ginseng teas (siberian, panax,
kudzu, knotweed)."
_As far as the rheumatoid arthritis goes the only herbs that are
really going to help are the Siberian ginseng and the Panax
ginsengs. Although high quality Panax ginsengs can be
stimulatory and if you are a female they are not good long term
since they raise testosterone.
_Kudzu and knotweed are not real or pseudoginsengs. They are
good herbs though. Kudzu is especially good for muscle tension
and to help prevent migraines. I primarily use knotweed for
hormone balance. This is the commercial source for resveratrol.
HERBS WITH MSM FOR INFECTION
_For infection, pau d' arco is quite safe. Even with extremely
high doses the side effects are only diarrhea and some thinning
of the blood.
_I don't know how much your friend is taking, but I generally
recommend 3 capsules 3 to 4 times daily and on an empty stomach
at least 20 minutes before meals. Taking it with a little sulfur
will increase its effectiveness. I prefer chaparral, or a little
MSM, watercress, onion, or garlic will also work.
_And depending on what kind of infection there may be better
herb choices.
MSM INFERIOR FOR INFLAMMATION
HTML https://www.curezone.org/forums/fm.asp?i=1713836
_"I thought MSM would take away any inflammation." Yucca root
and licorice root are better anti-inflammatories. And both build
up the adrenals, which produce the body's own steroidal
anti-inflammatories. One other thing you could try to elevate
ATP levels is the amino acid carnitine. It should be taken on an
empty stomach at least 30 minutes before meals.
HTML https://www.curezone.org/forums/fm.asp?i=1663092#i
_MSM ... helps to reduce inflammation and build tissues.
MSM FOR HAIR & NAILS
HTML https://www.curezone.org/forums/fm.asp?i=1454326
_MSM is a synthetic sulfur source containing 34% sulfur by
weight. It breaks down in to elemental sulfur in the body. From
there the sulfur is used for various purposes including the
formation of the protein keratin, which is composed of double
sulfur bonds. So yes, it helps with growth. Same applies to
hair.
_The reason it has not really been mentioned is because sulfur
deficiencies are very uncommon. So many of the foods we eat
contain sulfur, and some common ones such as onions and garlic
are high in sulfur.
_Silica is common in insoluble fibers, but unlike sulfur the
body's ability to absorb silica declines with age. So
supplementing or restoring stomach acidity to allow for its
proper absorption becomes very important.
HTML https://www.curezone.org/forums/fm.asp?i=1455842
_Deficiencies are rare, but extra sulfur does promote growth. It
would be like saying water deficiencies are rare, but we still
benefit by the ingestion of more water.
_Sulfur is used for many purposes in the body, such as insulin
formation and detoxification. Production of hair and nails is
not a major priority for the body. So we get plenty of sulfur in
the diet for the really important functions of the body. What is
left over goes to hair and nail growth. Taking the MSM just
provides additional sulfur for the less important functions.
HTML https://www.curezone.org/forums/fm.asp?i=1571761
_A couple of supplements that can help regrow hair are the herb
fo ti (he shou wu), and the supplements MSM (a sulfur source)
and tyrosine (an amino acid).
HTML https://www.curezone.org/forums/fm.asp?i=1768955#i
_MSM will stimulate hair growth.
MSM FOR STRETCH MARKS
HTML https://www.curezone.org/forums/fm.asp?i=1797364#i
_Sulfur sources such as MSM can help. But silica and vitamin C
sources are more important since sulfur is common in the diet.
Collagen and elastin stimulators such as gotu kola also help.
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