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       #Post#: 1677--------------------------------------------------
       CDC Confirms Second Human H5 Bird Flu Case in Michigan; Third Ca
       se Tied to Dairy Outbreak
       By: jlayman Date: May 30, 2024, 1:32 pm
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       Full text of CDC statement:
       CDC Confirms Second Human H5 Bird Flu Case in Michigan; Third
       Case Tied to Dairy Outbreak
       Risk to general public remains low
       May 30, 2024 – A second human case of highly pathogenic
       avian influenza (HPAI) A(H5) virus infection has been identified
       in the state of Michigan. This is the third human case
       associated with an ongoing multistate outbreak of A(H5N1) in
       U.S. dairy cows. None of the three cases are associated with the
       others. As with the previous two cases (one in Texas, one in
       Michigan), the person is a dairy farm worker with exposure to
       infected cows, making this another instance of probable
       cow-to-person spread. This is the first human case of H5 in the
       United States to report more typical symptoms of acute
       respiratory illness associated with influenza virus infection,
       including A(H5N1) viruses. [My note: Patient Zero?] CDC
       continues to closely monitor available data from influenza
       surveillance systems , particularly in affected states, and
       there has been no sign of unusual influenza activity in people,
       including no increase in emergency room visits for influenza and
       no increase in laboratory detection of human influenza cases.
       Based on the information available at this time, this case does
       not change CDC’s current A(H5N1) bird flu human health
       risk assessment for the U.S. general public because all three
       sporadic cases had direct contact with infected cows. Risk
       depends on exposure, and in this case, the relevant exposure is
       to infected animals. The risk to members of the general public
       who do not have exposure to infected animals remains low.
       However, this development underscores the importance of
       recommended precautions in people with exposure to infected or
       potentially infected animals. People with close or prolonged,
       unprotected exposures to infected birds or other animals
       (including livestock), or to environments contaminated by
       infected birds or other infected animals, are at greater risk of
       infection and should take precautions.
       Case Background
       A dairy worker with exposure to H5N1-infected cows (at a
       different farm from the case last week) reported symptoms to
       local health officials. The patient reported upper respiratory
       tract symptoms including cough without fever, and eye discomfort
       with watery discharge.  The patient was given antiviral
       treatment with oseltamivir, is isolating at home, and their
       symptoms are resolving. Household contacts of the patient have
       not developed symptoms, are being monitored for illness, and
       have been offered oseltamivir. No other workers at the same farm
       have reported symptoms, and all staff are being monitored. There
       is no indication of person-to-person spread of A(H5N1) viruses
       at this time.
       Specimens were collected from the patient; one of which was
       positive for influenza A(H5) virus using the CDC test at the
       state health department laboratory. The specimens were forwarded
       to CDC for further testing. They were received on May 29, and
       testing results that night confirmed A(H5) virus infection.
       Michigan was then notified of the results.
       The designation of the influenza virus neuraminidase (the N in
       the subtype) is pending genetic sequencing at CDC and results
       will be made available within 1-2 days, if successful.
       Additional genetic analysis will look for any changes to the
       virus that could change the agency’s risk assessment.
       CDC Activities and Risk Assessment
       This case was detected through Michigan’s active
       monitoring program for people exposed to infected livestock, in
       collaboration with CDC. The identification of an additional case
       of H5 is not surprising and shows the importance of a proactive
       public health response. Given the extent of the spread of this
       virus in dairy cows, additional human cases in people with
       higher risk exposures would not be surprising. A CDC priority
       right now is to prevent additional cases of A(H5N1) infections
       in dairy herd workers, who are at higher risk of exposure. CDC
       has previously provided updated interim recommendations for
       worker protection to include those who work with dairy cows and
       asked states to provide personal protective equipment to
       farmworkers. In addition, the agency is conducting ongoing
       outreach to groups representing farmworkers.
       CDC Recommendations
       - People should wear recommended personal protective equipment
       when interacting with infected or potentially infected animals
       and monitor their health for 10 days after their most recent
       exposure. Learn more about CDC’s recommendations for
       worker protection and use of personal protective equipment
       (PPE).
       - People should avoid close, long, or unprotected exposures to
       sick or dead animals, including wild birds, poultry, other
       domesticated birds, and other wild or domesticated animals
       (including cows).
       - People should also avoid unprotected exposures to animal poop,
       bedding (litter), unpasteurized (“raw”) milk, or
       materials that have been touched by, or close to, birds or other
       animals with suspected or confirmed A(H5N1) virus.
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